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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 2
2005 4
2006 7
2007 2
2008 5
2009 8
2010 9
2011 6
2012 3
2013 4
2014 1
2015 9
2016 4
2017 5
2018 4
2019 4
2020 2
2021 5
2022 1
2024 0

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78 results

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Page 1
Probing biological mechanisms with chemical tools.
Kang C, Keller TH. Kang C, et al. Among authors: keller th. Pharmacol Res. 2020 Mar;153:104656. doi: 10.1016/j.phrs.2020.104656. Epub 2020 Jan 18. Pharmacol Res. 2020. PMID: 31962154 Review.
Zika Virus Protease: An Antiviral Drug Target.
Kang C, Keller TH, Luo D. Kang C, et al. Among authors: keller th. Trends Microbiol. 2017 Oct;25(10):797-808. doi: 10.1016/j.tim.2017.07.001. Epub 2017 Aug 5. Trends Microbiol. 2017. PMID: 28789826 Review.
A practical view of 'druggability'.
Keller TH, Pichota A, Yin Z. Keller TH, et al. Curr Opin Chem Biol. 2006 Aug;10(4):357-61. doi: 10.1016/j.cbpa.2006.06.014. Epub 2006 Jun 30. Curr Opin Chem Biol. 2006. PMID: 16814592 Review.
Anti-infectives: can cellular screening deliver?
Keller TH, Shi PY, Wang QY. Keller TH, et al. Curr Opin Chem Biol. 2011 Aug;15(4):529-33. doi: 10.1016/j.cbpa.2011.06.007. Epub 2011 Jun 30. Curr Opin Chem Biol. 2011. PMID: 21723774 Review.
Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase.
Anantharajan J, Baburajendran N, Lin G, Loh YY, Xu W, Ahmad NHB, Liu S, Jansson AE, Kuan JWL, Ng EY, Yeo YK, Hung AW, Joy J, Hill J, Ford HL, Zhao R, Keller TH, Kang C. Anantharajan J, et al. Among authors: keller th. Protein Sci. 2022 Feb;31(2):422-431. doi: 10.1002/pro.4234. Epub 2021 Nov 18. Protein Sci. 2022. PMID: 34761455 Free PMC article.
Strategic Design of Catalytic Lysine-Targeting Reversible Covalent BCR-ABL Inhibitors*.
Quach D, Tang G, Anantharajan J, Baburajendran N, Poulsen A, Wee JLK, Retna P, Li R, Liu B, Tee DHY, Kwek PZ, Joy JK, Yang WQ, Zhang CJ, Foo K, Keller TH, Yao SQ. Quach D, et al. Among authors: keller th. Angew Chem Int Ed Engl. 2021 Jul 26;60(31):17131-17137. doi: 10.1002/anie.202105383. Epub 2021 Jun 24. Angew Chem Int Ed Engl. 2021. PMID: 34008286
Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3.
Huang C, Liew SS, Lin GR, Poulsen A, Ang MJY, Chia BCS, Chew SY, Kwek ZP, Wee JLK, Ong EH, Retna P, Baburajendran N, Li R, Yu W, Koh-Stenta X, Ngo A, Manesh S, Fulwood J, Ke Z, Chung HH, Sepramaniam S, Chew XH, Dinie N, Lee MA, Chew YS, Low CB, Pendharkar V, Manoharan V, Vuddagiri S, Sangthongpitag K, Joy J, Matter A, Hill J, Keller TH, Foo K. Huang C, et al. Among authors: keller th. ACS Med Chem Lett. 2019 May 23;10(6):978-984. doi: 10.1021/acsmedchemlett.9b00170. eCollection 2019 Jun 13. ACS Med Chem Lett. 2019. PMID: 31223458 Free PMC article.
Discovery and Optimization of a Porcupine Inhibitor.
Duraiswamy AJ, Lee MA, Madan B, Ang SH, Tan ES, Cheong WW, Ke Z, Pendharkar V, Ding LJ, Chew YS, Manoharan V, Sangthongpitag K, Alam J, Poulsen A, Ho SY, Virshup DM, Keller TH. Duraiswamy AJ, et al. Among authors: keller th. J Med Chem. 2015 Aug 13;58(15):5889-99. doi: 10.1021/acs.jmedchem.5b00507. Epub 2015 Jul 16. J Med Chem. 2015. PMID: 26110200
78 results