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Year | Number of Results |
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2019 | 3 |
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Page 1
Inhibitor-Induced Dimerization of an Essential Oxidoreductase from African Trypanosomes.
Angew Chem Int Ed Engl. 2019 Mar 11;58(11):3640-3644. doi: 10.1002/anie.201810470. Epub 2019 Jan 30.
Angew Chem Int Ed Engl. 2019.
PMID: 30605929
Naphthoquinones as Covalent Reversible Inhibitors of Cysteine Proteases-Studies on Inhibition Mechanism and Kinetics.
Klein P, Barthels F, Johe P, Wagner A, Tenzer S, Distler U, Le TA, Schmid P, Engel V, Engels B, Hellmich UA, Opatz T, Schirmeister T.
Klein P, et al. Among authors: le ta.
Molecules. 2020 Apr 28;25(9):2064. doi: 10.3390/molecules25092064.
Molecules. 2020.
PMID: 32354191
Free PMC article.
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Product-oriented chemical surface modification of a levansucrase (SacB) via an ene-type reaction.
Ortiz-Soto ME, Ertl J, Mut J, Adelmann J, Le TA, Shan J, Teßmar J, Schlosser A, Engels B, Seibel J.
Ortiz-Soto ME, et al. Among authors: le ta.
Chem Sci. 2018 May 22;9(24):5312-5321. doi: 10.1039/c8sc01244j. eCollection 2018 Jun 28.
Chem Sci. 2018.
PMID: 30009003
Free PMC article.
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Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt.
Uhlenbrock N, Smith S, Weisner J, Landel I, Lindemann M, Le TA, Hardick J, Gontla R, Scheinpflug R, Czodrowski P, Janning P, Depta L, Quambusch L, Müller MP, Engels B, Rauh D.
Uhlenbrock N, et al. Among authors: le ta.
Chem Sci. 2019 Feb 13;10(12):3573-3585. doi: 10.1039/c8sc05212c. eCollection 2019 Mar 28.
Chem Sci. 2019.
PMID: 30996949
Free PMC article.
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A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure.
Eltschkner S, Kehrein J, Le TA, Davoodi S, Merget B, Basak S, Weinrich JD, Schiebel J, Tonge PJ, Engels B, Sotriffer C, Kisker C.
Eltschkner S, et al. Among authors: le ta.
ACS Infect Dis. 2021 Apr 9;7(4):746-758. doi: 10.1021/acsinfecdis.0c00437. Epub 2021 Mar 12.
ACS Infect Dis. 2021.
PMID: 33710875
Free PMC article.
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Tuning the Product Spectrum of a Glycoside Hydrolase Enzyme by a Combination of Site-Directed Mutagenesis and Tyrosine-Specific Chemical Modification.
Ertl J, Ortiz-Soto ME, Le TA, Bechold J, Shan J, Teßmar J, Engels B, Seibel J.
Ertl J, et al. Among authors: le ta.
Chemistry. 2019 May 7;25(26):6533-6541. doi: 10.1002/chem.201900576. Epub 2019 Mar 26.
Chemistry. 2019.
PMID: 30820987
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