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Variation between Canadian centres in the uptake of treatment for hepatitis C by patients coinfected with HIV: a prospective cohort study.
Young J, Potter M, Cox J, Cooper C, Gill J, Hull M, Walmsley S, Klein MB. Young J, et al. CMAJ Open. 2013 Sep 24;1(3):E106-14. doi: 10.9778/cmajo.20130009. eCollection 2013 Sep. CMAJ Open. 2013. PMID: 25077109 Free PMC article.
BACKGROUND: Uptake of treatment for hepatitis C virus (HCV) is low in Canada despite its publicly funded health care system. We explored the uptake of HCV treatment within the Canadian Co-infection Cohort to determine if some treatment centres have been more …
BACKGROUND: Uptake of treatment for hepatitis C virus (HCV) is low in Canada despite its publicly funded health care system. We explored the …
Mortality in HIV-hepatitis C co-infected patients in Canada compared to the general Canadian population (2003-2013).
Klein MB, Rollet-Kurhajec KC, Moodie EE, Yaphe S, Tyndall M, Walmsley S, Gill J, Martel-Laferriere V, Cooper C; Canadian Co-infection Cohort Investigators. Klein MB, et al. AIDS. 2014 Aug 24;28(13):1957-65. doi: 10.1097/QAD.0000000000000377. AIDS. 2014. PMID: 25259703
OBJECTIVE: Recent studies suggest all-cause mortality in HIV mono-infected patients approaches that of the general population. We aimed to compare participants in the Canadian Co-infection Cohort to the general population to determine if co-infected patients …
OBJECTIVE: Recent studies suggest all-cause mortality in HIV mono-infected patients approaches that of the general population. We aimed to c …
Food Insecurity in HIV-Hepatitis C Virus Co-infected Individuals in Canada: The Importance of Co-morbidities.
Cox J, Hamelin AM, McLinden T, Moodie EE, Anema A, Rollet-Kurhajec KC, Paradis G, Rourke SB, Walmsley SL, Klein MB; Canadian Co-infection Cohort Investigators. Cox J, et al. AIDS Behav. 2017 Mar;21(3):792-802. doi: 10.1007/s10461-016-1326-9. AIDS Behav. 2017. PMID: 26912217 Free PMC article.
While research has begun addressing food insecurity (FI) in HIV-positive populations, knowledge regarding FI among individuals living with HIV-hepatitis C virus (HCV) co-infection is limited. This exploratory study examines sociodemographic, socioeconomic, be …
While research has begun addressing food insecurity (FI) in HIV-positive populations, knowledge regarding FI among individuals living with H …
Association between depressive symptoms, CD4 count and HIV viral suppression among HIV-HCV co-infected people.
Aibibula W, Cox J, Hamelin AM, Moodie EEM, Anema A, Klein MB, Brassard P; Canadian Co-infection Cohort Investigators. Aibibula W, et al. AIDS Care. 2018 May;30(5):643-649. doi: 10.1080/09540121.2018.1431385. Epub 2018 Jan 28. AIDS Care. 2018. PMID: 29374972
However, no prior studies assessed this association exclusively among people co-infected with HIV-hepatitis C virus (HCV). While people with HIV only and those with HIV-HCV co-infection share many characteristics, co-infected people may become more susceptible to th …
However, no prior studies assessed this association exclusively among people co-infected with HIV-hepatitis C virus (HCV). While people with …
Hepatitis C virus cure does not impact kidney function decline in HIV co-infected patients.
Rossi C, Saeed S, Cox J, Vachon ML, Martel-Laferrière V, Walmsley SL, Cooper C, Gill MJ, Hull M, Moodie EEM, Klein MB; Canadian Co-Infection Cohort Investigators. Rossi C, et al. AIDS. 2018 Mar 27;32(6):751-759. doi: 10.1097/QAD.0000000000001750. AIDS. 2018. PMID: 29369156 Free PMC article.
OBJECTIVE: To examine the impact of sustained virologic response (SVR) and illicit (injection and noninjection) drug use on kidney function among hepatitis C virus (HCV) and HIV co-infected individuals. DESIGN: Longitudinal observational cohort study of HCV-HIV co-infected …
OBJECTIVE: To examine the impact of sustained virologic response (SVR) and illicit (injection and noninjection) drug use on kidney function …
Impact of Food Insecurity on Depressive Symptoms Among HIV-HCV Co-infected People.
Aibibula W, Cox J, Hamelin AM, Moodie EEM, Naimi AI, McLinden T, Klein MB, Brassard P; Canadian Co-infection Cohort Investigators. Aibibula W, et al. AIDS Behav. 2017 Dec;21(12):3464-3472. doi: 10.1007/s10461-017-1942-z. AIDS Behav. 2017. PMID: 29076031
Our objective was to examine to what extent this association holds among HIV-hepatitis C virus (HCV) co-infected people. We used data from a prospective cohort study of HIV-HCV co-infected people in Canada. FI was measured using the ten-item adult scale of Health Canada's …
Our objective was to examine to what extent this association holds among HIV-hepatitis C virus (HCV) co-infected people. We used data from a …
Opioid use and risk of liver fibrosis in HIV/hepatitis C virus-coinfected patients in Canada.
Brunet L, Moodie EE, Cox J, Gill J, Cooper C, Walmsley S, Rachlis A, Hull M, Klein MB; Canadian Coinfection Cohort Study Investigators. Brunet L, et al. HIV Med. 2016 Jan;17(1):36-45. doi: 10.1111/hiv.12279. Epub 2015 Jul 3. HIV Med. 2016. PMID: 26140381 Free article.
METHODS: We conducted a cross-sectional descriptive analysis of the Canadian Co-infection Cohort Study data to characterize opioid use. ...
METHODS: We conducted a cross-sectional descriptive analysis of the Canadian Co-infection Cohort Study data to c …
Real-world impact of direct acting antiviral therapy on health-related quality of life in HIV/Hepatitis C co-infected individuals.
Saeed S, Moodie EEM, Strumpf E, Gill J, Wong A, Cooper C, Walmsley S, Hull M, Martel-Laferriere V, Klein MB; Canadian Co-Infection Cohort Study Investigators. Saeed S, et al. J Viral Hepat. 2018 Dec;25(12):1507-1514. doi: 10.1111/jvh.12985. Epub 2018 Sep 27. J Viral Hepat. 2018. PMID: 30141236
We investigated the real-world impact of oral DAA therapy on HR-QoL among individuals coinfected with HIV/HCV. We used data from the Canadian HIV/HCV Co-Infection Cohort Study that prospectively follows 1795 participants from 18 centres. ...
We investigated the real-world impact of oral DAA therapy on HR-QoL among individuals coinfected with HIV/HCV. We used data from the Cana
Cohort Profile: HAART Observational Medical Evaluation and Research (HOMER) cohort.
Patterson S, Cescon A, Samji H, Cui Z, Yip B, Lepik KJ, Moore D, Lima VD, Nosyk B, Harrigan PR, Montaner JS, Shannon K, Wood E, Hogg RS. Patterson S, et al. Int J Epidemiol. 2015 Feb;44(1):58-67. doi: 10.1093/ije/dyu046. Epub 2014 Mar 17. Int J Epidemiol. 2015. PMID: 24639444 Free PMC article.
CD4 cell count, plasma HIV viral load, AIDS-defining illness, hepatitis C co-infection, mortality) and treatment variables (e.g. HAART regimens, date of treatment initiation, treatment interruptions, adherence data, resistance testing). ...The HOMER cohort collabora …
CD4 cell count, plasma HIV viral load, AIDS-defining illness, hepatitis C co-infection, mortality) and treatment variables (e. …
Favourable IFNL3 genotypes are associated with spontaneous clearance and are differentially distributed in Aboriginals in Canadian HIV-hepatitis C co-infected individuals.
Moqueet N, Infante-Rivard C, Platt RW, Young J, Cooper C, Hull M, Walmsley S, Klein MB; Canadian Co-Infection Study Investigators. Moqueet N, et al. Int J Mol Sci. 2015 Mar 20;16(3):6496-512. doi: 10.3390/ijms16036496. Int J Mol Sci. 2015. PMID: 25803108 Free PMC article.
Canadian Aboriginals are reported to clear Hepatitis C (HCV) more frequently. We tested the association of spontaneous clearance and three single nucleotide polymorphisms (SNPs) near the Interferon-lambda 3 (IFNL3) gene (rs12979860, rs8099917, functional variant rs8103142)
Canadian Aboriginals are reported to clear Hepatitis C (HCV) more frequently. We tested the association of spontaneous clearance and
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