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23 results

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Page 1
The turning point of COVID-19 severity is associated with a unique circulating neutrophil gene signature.
Fuzo CA, Fraga-Silva TFC, Maruyama SR, Bastos VAF, Rogerio LA, Takamiya NT, da Silva-Neto PV, Pimentel VE, Toro DM, Pérez MM, de Carvalho JCS, Carmona-Garcia I, Oliveira CNS, Degiovani AM, Ostini FM, Constant LF, de Amorim AP, Vilar FC, Feitosa MR, Parra RS, da Rocha JJR, Feres O, Gaspar GG, Viana AL, Fernandes APM, Santos IKFM, Russo EMS, Cardoso CRB, Sorgi CA, Faccioli LH, Bonato VLD, Dias-Baruffi M; ImmunoCOVID study group. Fuzo CA, et al. Among authors: fraga silva tfc. Immunology. 2023 Jul;169(3):323-343. doi: 10.1111/imm.13631. Epub 2023 Mar 8. Immunology. 2023. PMID: 36740582
The IgG glycome of SARS-CoV-2 infected individuals reflects disease course and severity.
Siekman SL, Pongracz T, Wang W, Nouta J, Kremsner PG, da Silva-Neto PV, Esen M, Kreidenweiss A, Held J, Trapé ÁA, Fendel R, de Miranda Santos IKF, Wuhrer M; ImmunoCovid Consortium. Siekman SL, et al. Front Immunol. 2022 Oct 18;13:993354. doi: 10.3389/fimmu.2022.993354. eCollection 2022. Front Immunol. 2022. PMID: 36389824 Free PMC article.
Cytokine storm in individuals with severe COVID-19 decreases endothelial cell antioxidant defense via downregulation of the Nrf2 transcriptional factor.
Rodrigues D, Machado MR, Alves JV, Fraga-Silva TFC, Martins RB, Campos LCB, Francisco DF, Couto AES, Bonato VLD, Arruda E, Becari C, Auxiliadora-Martins M, Louzada-Júnior P, Costa RM, Tostes RC. Rodrigues D, et al. Among authors: fraga silva tfc. Am J Physiol Heart Circ Physiol. 2023 Aug 1;325(2):H252-H263. doi: 10.1152/ajpheart.00096.2023. Epub 2023 Jun 16. Am J Physiol Heart Circ Physiol. 2023. PMID: 37327001 Free PMC article.
Acetylcholine, Fatty Acids, and Lipid Mediators Are Linked to COVID-19 Severity.
Pérez MM, Pimentel VE, Fuzo CA, da Silva-Neto PV, Toro DM, Fraga-Silva TFC, Gardinassi LG, Oliveira CNS, Souza COS, Torre-Neto NT, de Carvalho JCS, De Leo TC, Nardini V, Feitosa MR, Parra RS, da Rocha JJR, Feres O, Vilar FC, Gaspar GG, Constant LF, Ostini FM, Degiovani AM, Amorim AP, Viana AL, Fernandes APM, Maruyama SR, Russo EMS, Santos IKFM, Bonato VLD, Cardoso CRB, Sorgi CA, Dias-Baruffi M, Faccioli LH; ImmunoCOVID Brazilian Research Consortium. Pérez MM, et al. Among authors: fraga silva tfc. J Immunol. 2022 Jul 15;209(2):250-261. doi: 10.4049/jimmunol.2200079. Epub 2022 Jun 29. J Immunol. 2022. PMID: 35768148
Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage.
Costa TJ, Potje SR, Fraga-Silva TFC, da Silva-Neto JA, Barros PR, Rodrigues D, Machado MR, Martins RB, Santos-Eichler RA, Benatti MN, de Sá KSG, Almado CEL, Castro ÍA, Pontelli MC, Serra L, Carneiro FS, Becari C, Louzada-Junior P, Oliveira RDR, Zamboni DS, Arruda E, Auxiliadora-Martins M, Giachini FRC, Bonato VLD, Zachara NE, Bomfim GF, Tostes RC. Costa TJ, et al. Among authors: fraga silva tfc. Vascul Pharmacol. 2022 Feb;142:106946. doi: 10.1016/j.vph.2021.106946. Epub 2021 Nov 25. Vascul Pharmacol. 2022. PMID: 34838735 Free PMC article.
Divergent androgenic modulation of SARS-CoV-2 infection cooperates with dysregulated immune response to dictate worse COVID-19 outcomes in men.
Duarte-Silva M, Oliveira CNS, Fuzo C, Silva-Neto PV, Toro DM, Pimentel VE, Pérez MM, Fraga-Silva TFC, Carvalho JCS, Neto FMS, Júnior RBM, Arruda E, Vilar FC, Degiovani AM, Ostini FM, Feitosa MR, Parra RS, Gaspar GG, Rocha JJR, Feres O, Fernandes APM, Maruyama SR, Russo EMS, Bonato VLD, Santos IKFM, Sorgi CA, Dias-Baruffi M, Faccioli LH, Cardoso CRB; ImmunoCOVID Brazilian Research Consortium. Duarte-Silva M, et al. Among authors: fraga silva tfc. Brain Behav Immun. 2023 Nov;114:275-286. doi: 10.1016/j.bbi.2023.08.026. Epub 2023 Aug 28. Brain Behav Immun. 2023. PMID: 37648004
The Severity of COVID-19 Affects the Plasma Soluble Levels of the Immune Checkpoint HLA-G Molecule.
Cordeiro JFC, Fernandes TM, Toro DM, da Silva-Neto PV, Pimentel VE, Pérez MM, de Carvalho JCS, Fraga-Silva TFC, Oliveira CNS, Argolo JGM, Degiovani AM, Ostini FM, Puginna EF, da Silva JS, Santos IKFM, Bonato VLD, Cardoso CRB, Dias-Baruffi M, Faccioli LH, Donadi EA, Sorgi CA, Fernandes APM, On Behalf Of The Immunocovid Study Group. Cordeiro JFC, et al. Among authors: fraga silva tfc. Int J Mol Sci. 2022 Aug 27;23(17):9736. doi: 10.3390/ijms23179736. Int J Mol Sci. 2022. PMID: 36077133 Free PMC article.
Airway epithelial cells and macrophages trigger IL-6-CD95/CD95L axis and mediate initial immunopathology of COVID-19.
Fraga-Silva TFC, Cipriano UG, Fumagalli MJ, Correa GF, Fuzo CA, Dos-Santos D, Mestriner FLAC, Becari C, Teixeira-Carvalho A, Coelho-Dos-Reis J, Menegueti MG, Figueiredo LTM, Cunha LD, Martins-Filho OA, Dias-Baruffi M, Auxiliadora-Martins M, Tostes RC, Bonato VLD. Fraga-Silva TFC, et al. iScience. 2023 Oct 31;26(12):108366. doi: 10.1016/j.isci.2023.108366. eCollection 2023 Dec 15. iScience. 2023. PMID: 38047070 Free PMC article.
Heparin prevents in vitro glycocalyx shedding induced by plasma from COVID-19 patients.
Potje SR, Costa TJ, Fraga-Silva TFC, Martins RB, Benatti MN, Almado CEL, de Sá KSG, Bonato VLD, Arruda E, Louzada-Junior P, Oliveira RDR, Zamboni DS, Becari C, Auxiliadora-Martins M, Tostes RC. Potje SR, et al. Among authors: fraga silva tfc. Life Sci. 2021 Jul 1;276:119376. doi: 10.1016/j.lfs.2021.119376. Epub 2021 Mar 27. Life Sci. 2021. PMID: 33781826 Free PMC article.
Matrix Metalloproteinases on Severe COVID-19 Lung Disease Pathogenesis: Cooperative Actions of MMP-8/MMP-2 Axis on Immune Response through HLA-G Shedding and Oxidative Stress.
da Silva-Neto PV, do Valle VB, Fuzo CA, Fernandes TM, Toro DM, Fraga-Silva TFC, Basile PA, de Carvalho JCS, Pimentel VE, Pérez MM, Oliveira CNS, Rodrigues LC, Bastos VAF, Tella SOC, Martins RB, Degiovani AM, Ostini FM, Feitosa MR, Parra RS, Vilar FC, Gaspar GG, Rocha JJRD, Feres O, Arruda E, Maruyama SR, Russo EMS, Viana AL, Santos IKFM, Bonato VLD, Cardoso CRB, Tanus-Santos JE, Donadi EA, Faccioli LH, Dias-Baruffi M, Fernandes APM, Gerlach RF, Sorgi CA, On Behalf Of The Immunocovid Study Group. da Silva-Neto PV, et al. Among authors: fraga silva tfc. Biomolecules. 2022 Apr 19;12(5):604. doi: 10.3390/biom12050604. Biomolecules. 2022. PMID: 35625532 Free PMC article.
23 results