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Year Number of Results
2006 1
2007 2
2008 1
2009 2
2010 3
2011 1
2012 2
2013 1
2022 2
2023 1
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Page 1
2-(1H-Pyrazol-4-yl)acetic acids as CRTh2 antagonists.
Andrés M, Bravo M, Buil MA, Calbet M, Castro J, Domènech T, Eichhorn P, Ferrer M, Gómez E, Lehner MD, Moreno I, Roberts RS, Sevilla S. Andrés M, et al. Among authors: domenech t. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3349-53. doi: 10.1016/j.bmcl.2013.03.093. Epub 2013 Apr 2. Bioorg Med Chem Lett. 2013. PMID: 23601708
Pharmacological characterization of a novel peptide inhibitor of the Keap1-Nrf2 protein-protein interaction.
Aparici M, Bravo M, Calama E, García-González V, Domènech T, Córdoba M, Roger I, Cortijo J, Góngora-Benítez M, Paradís-Bas M, Collins B, Davis AM, Albericio F, Puig C. Aparici M, et al. Among authors: domenech t. Biochem Pharmacol. 2022 Oct;204:115226. doi: 10.1016/j.bcp.2022.115226. Epub 2022 Aug 24. Biochem Pharmacol. 2022. PMID: 36027928
Discovery of LAS101057: A Potent, Selective, and Orally Efficacious A2B Adenosine Receptor Antagonist.
Eastwood P, Esteve C, González J, Fonquerna S, Aiguadé J, Carranco I, Doménech T, Aparici M, Miralpeix M, Albertí J, Córdoba M, Fernández R, Pont M, Godessart N, Prats N, Loza MI, Cadavid MI, Nueda A, Vidal B. Eastwood P, et al. Among authors: domenech t. ACS Med Chem Lett. 2010 Dec 20;2(3):213-8. doi: 10.1021/ml100249e. eCollection 2011 Mar 10. ACS Med Chem Lett. 2010. PMID: 24900298 Free PMC article.
Discovery of a novel class of zwitterionic, potent, selective and orally active S1P₁ direct agonists.
Aguilar N, Mir M, Grima PM, López M, Segarra V, Esteban L, Moreno I, Godessart N, Tarrasón G, Domenech T, Vilella D, Armengol C, Córdoba M, Sabaté M, Casals D, Domínguez M. Aguilar N, et al. Among authors: domenech t. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7672-6. doi: 10.1016/j.bmcl.2012.09.110. Epub 2012 Oct 11. Bioorg Med Chem Lett. 2012. PMID: 23141913
Discovery and characterization of 4'-(2-furyl)-N-pyridin-3-yl-4,5'-bipyrimidin-2'-amine (LAS38096), a potent, selective, and efficacious A2B adenosine receptor antagonist.
Vidal B, Nueda A, Esteve C, Domenech T, Benito S, Reinoso RF, Pont M, Calbet M, López R, Cadavid MI, Loza MI, Cárdenas A, Godessart N, Beleta J, Warrellow G, Ryder H. Vidal B, et al. Among authors: domenech t. J Med Chem. 2007 May 31;50(11):2732-6. doi: 10.1021/jm061333v. Epub 2007 May 1. J Med Chem. 2007. PMID: 17469811
Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinol esters as potent and long-acting muscarinic antagonists with potential for minimal systemic exposure after inhaled administration: identification of (3R)-3-{[hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane bromide (aclidinium bromide).
Prat M, Fernández D, Buil MA, Crespo MI, Casals G, Ferrer M, Tort L, Castro J, Monleón JM, Gavaldà A, Miralpeix M, Ramos I, Doménech T, Vilella D, Antón F, Huerta JM, Espinosa S, López M, Sentellas S, González M, Albertí J, Segarra V, Cárdenas A, Beleta J, Ryder H. Prat M, et al. Among authors: domenech t. J Med Chem. 2009 Aug 27;52(16):5076-92. doi: 10.1021/jm900132z. J Med Chem. 2009. PMID: 19653626
Characterization of aclidinium bromide, a novel inhaled muscarinic antagonist, with long duration of action and a favorable pharmacological profile.
Gavaldà A, Miralpeix M, Ramos I, Otal R, Carreño C, Viñals M, Doménech T, Carcasona C, Reyes B, Vilella D, Gras J, Cortijo J, Morcillo E, Llenas J, Ryder H, Beleta J. Gavaldà A, et al. Among authors: domenech t. J Pharmacol Exp Ther. 2009 Nov;331(2):740-51. doi: 10.1124/jpet.109.151639. Epub 2009 Aug 26. J Pharmacol Exp Ther. 2009. PMID: 19710368 Free article.
13 results