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Combination therapy of bevacizumab with either S-1 and irinotecan or mFOLFOX6/CapeOX as first-line treatment of metastatic colorectal cancer (TRICOLORE): Exploratory analysis of RAS status and primary tumour location in a randomised, open-label, phase III, non-inferiority trial.
Denda T, Takashima A, Gamoh M, Iwanaga I, Komatsu Y, Takahashi M, Nakamura M, Ohori H, Sakashita A, Tsuda M, Kobayashi Y, Baba H, Kotake M, Ishioka C, Yamada Y, Sato A, Yuki S, Morita S, Takahashi S, Yamaguchi T, Shimada K. Denda T, et al. Eur J Cancer. 2021 Sep;154:296-306. doi: 10.1016/j.ejca.2021.06.013. Epub 2021 Jul 22. Eur J Cancer. 2021. PMID: 34304054 Free article. Clinical Trial.
Study protocol of the TRICOLORE trial: a randomized phase III study of oxaliplatin-based chemotherapy versus combination chemotherapy with S-1, irinotecan, and bevacizumab as first-line therapy for metastatic colorectal cancer.
Komatsu Y, Ishioka C, Shimada K, Yamada Y, Gamoh M, Sato A, Yamaguchi T, Yuki S, Morita S, Takahashi S, Goto R, Kurihara M. Komatsu Y, et al. BMC Cancer. 2015 Sep 9;15:626. doi: 10.1186/s12885-015-1630-1. BMC Cancer. 2015. PMID: 26353772 Free PMC article. Clinical Trial.