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Page 1
Polλ promotes microhomology-mediated end-joining.
Chandramouly G, Jamsen J, Borisonnik N, Tyagi M, Calbert ML, Tredinnick T, Ozdemir AY, Kent T, Demidova EV, Arora S, Wilson SH, Pomerantz RT. Chandramouly G, et al. Among authors: kent t. Nat Struct Mol Biol. 2023 Jan;30(1):107-114. doi: 10.1038/s41594-022-00895-4. Epub 2022 Dec 19. Nat Struct Mol Biol. 2023. PMID: 36536104 Free PMC article.
Author Correction: Polλ promotes microhomology-mediated end-joining.
Chandramouly G, Jamsen J, Borisonnik N, Tyagi M, Calbert ML, Tredinnick T, Ozdemir AY, Kent T, Demidova EV, Arora S, Wilson SH, Pomerantz RT. Chandramouly G, et al. Among authors: kent t. Nat Struct Mol Biol. 2023 Jul;30(7):1048. doi: 10.1038/s41594-023-00993-x. Nat Struct Mol Biol. 2023. PMID: 37059901 No abstract available.
How RNA transcripts coordinate DNA recombination and repair.
McDevitt S, Rusanov T, Kent T, Chandramouly G, Pomerantz RT. McDevitt S, et al. Among authors: kent t. Nat Commun. 2018 Mar 15;9(1):1091. doi: 10.1038/s41467-018-03483-7. Nat Commun. 2018. PMID: 29545568 Free PMC article.
Polθ reverse transcribes RNA and promotes RNA-templated DNA repair.
Chandramouly G, Zhao J, McDevitt S, Rusanov T, Hoang T, Borisonnik N, Treddinick T, Lopezcolorado FW, Kent T, Siddique LA, Mallon J, Huhn J, Shoda Z, Kashkina E, Brambati A, Stark JM, Chen XS, Pomerantz RT. Chandramouly G, et al. Among authors: kent t. Sci Adv. 2021 Jun 11;7(24):eabf1771. doi: 10.1126/sciadv.abf1771. Print 2021 Jun. Sci Adv. 2021. PMID: 34117057 Free PMC article.
Polymerase θ-helicase efficiently unwinds DNA and RNA-DNA hybrids.
Ozdemir AY, Rusanov T, Kent T, Siddique LA, Pomerantz RT. Ozdemir AY, et al. Among authors: kent t. J Biol Chem. 2018 Apr 6;293(14):5259-5269. doi: 10.1074/jbc.RA117.000565. Epub 2018 Feb 14. J Biol Chem. 2018. PMID: 29444826 Free PMC article.
Molecular basis of microhomology-mediated end-joining by purified full-length Polθ.
Black SJ, Ozdemir AY, Kashkina E, Kent T, Rusanov T, Ristic D, Shin Y, Suma A, Hoang T, Chandramouly G, Siddique LA, Borisonnik N, Sullivan-Reed K, Mallon JS, Skorski T, Carnevale V, Murakami KS, Wyman C, Pomerantz RT. Black SJ, et al. Among authors: kent t. Nat Commun. 2019 Sep 27;10(1):4423. doi: 10.1038/s41467-019-12272-9. Nat Commun. 2019. PMID: 31562312 Free PMC article.
4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress.
Calbert ML, Chandramouly G, Adams CM, Saez-Ayala M, Kent T, Tyagi M, Ayyadevara VSSA, Wang Y, Krais JJ, Gordon J, Atkins J, Toma MM, Betzi S, Boghossian AS, Rees MG, Ronan MM, Roth JA, Goldman AR, Gorman N, Mitra R, Childers WE, Graña X, Skorski T, Johnson N, Hurtz C, Morelli X, Eischen CM, Pomerantz RT. Calbert ML, et al. Among authors: kent t. Mol Cancer Ther. 2023 Dec 8. doi: 10.1158/1535-7163.MCT-23-0487. Online ahead of print. Mol Cancer Ther. 2023. PMID: 38064712
23 results