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The peptide transporter PEPT1 is expressed in distal colon in rodents and humans and contributes to water absorption.
Wuensch T, Schulz S, Ullrich S, Lill N, Stelzl T, Rubio-Aliaga I, Loh G, Chamaillard M, Haller D, Daniel H. Wuensch T, et al. Among authors: stelzl t. Am J Physiol Gastrointest Liver Physiol. 2013 Jul 1;305(1):G66-73. doi: 10.1152/ajpgi.00491.2012. Epub 2013 May 9. Am J Physiol Gastrointest Liver Physiol. 2013. PMID: 23660505 Free article.
Mice lacking the intestinal peptide transporter display reduced energy intake and a subtle maldigestion/malabsorption that protects them from diet-induced obesity.
Kolodziejczak D, Spanier B, Pais R, Kraiczy J, Stelzl T, Gedrich K, Scherling C, Zietek T, Daniel H. Kolodziejczak D, et al. Among authors: stelzl t. Am J Physiol Gastrointest Liver Physiol. 2013 May 15;304(10):G897-907. doi: 10.1152/ajpgi.00160.2012. Epub 2013 Mar 14. Am J Physiol Gastrointest Liver Physiol. 2013. PMID: 23494121 Free article.