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Page 1
Development of Small Molecule Chimeras That Recruit AhR E3 Ligase to Target Proteins.
ACS Chem Biol. 2019 Dec 20;14(12):2822-2832. doi: 10.1021/acschembio.9b00704. Epub 2019 Oct 16.
ACS Chem Biol. 2019.
PMID: 31580635
Targeted Protein Degradation by Chimeric Compounds using Hydrophobic E3 Ligands and Adamantane Moiety.
Shoda T, Ohoka N, Tsuji G, Fujisato T, Inoue H, Demizu Y, Naito M, Kurihara M.
Shoda T, et al. Among authors: fujisato t.
Pharmaceuticals (Basel). 2020 Feb 25;13(3):34. doi: 10.3390/ph13030034.
Pharmaceuticals (Basel). 2020.
PMID: 32106507
Free PMC article.
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Synthesis and evaluation of raloxifene derivatives as a selective estrogen receptor down-regulator.
Shoda T, Kato M, Fujisato T, Misawa T, Demizu Y, Inoue H, Naito M, Kurihara M.
Shoda T, et al. Among authors: fujisato t.
Bioorg Med Chem. 2016 Jul 1;24(13):2914-2919. doi: 10.1016/j.bmc.2016.04.068. Epub 2016 May 7.
Bioorg Med Chem. 2016.
PMID: 27185013
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Tamoxifen and Fulvestrant Hybrids Showed Potency as Selective Estrogen Receptor Down-Regulators.
Shoda T, Kato M, Fujisato T, Demizu Y, Inoue H, Naito M, Kurihara M.
Shoda T, et al. Among authors: fujisato t.
Med Chem. 2017;13(3):206-213. doi: 10.2174/1573406412666160805101408.
Med Chem. 2017.
PMID: 27494098
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Design and synthesis of novel selective estrogen receptor degradation inducers based on the diphenylheptane skeleton.
Misawa T, Fujisato T, Kanda Y, Ohoka N, Shoda T, Yorioka M, Makishima M, Sekino Y, Naito M, Demizu Y, Kurihara M.
Misawa T, et al. Among authors: fujisato t.
Medchemcomm. 2016 Dec 8;8(1):239-246. doi: 10.1039/c6md00553e. eCollection 2017 Jan 1.
Medchemcomm. 2016.
PMID: 30108709
Free PMC article.
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Synthesis and evaluation of tamoxifen derivatives with a long alkyl side chain as selective estrogen receptor down-regulators.
Shoda T, Kato M, Harada R, Fujisato T, Okuhira K, Demizu Y, Inoue H, Naito M, Kurihara M.
Shoda T, et al. Among authors: fujisato t.
Bioorg Med Chem. 2015 Jul 1;23(13):3091-6. doi: 10.1016/j.bmc.2015.05.002. Epub 2015 May 11.
Bioorg Med Chem. 2015.
PMID: 26003343
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