Takashi Kurohara - Search Results

Year	Number of Results
2014	1
2019	3
2021	5
2022	5
2023	5
2024	2

1

Cancer-Cell-Selective Targeting by Arylcyclopropylamine-Vorinostat Conjugates.

Ota Y, Itoh Y, Kurohara T, Singh R, Elboray EE, Hu C, Zamani F, Mukherjee A, Takada Y, Yamashita Y, Morita M, Horinaka M, Sowa Y, Masuda M, Sakai T, Suzuki T. Ota Y, et al. Among authors: kurohara t. ACS Med Chem Lett. 2022 Sep 12;13(10):1568-1573. doi: 10.1021/acsmedchemlett.2c00126. eCollection 2022 Oct 13. ACS Med Chem Lett. 2022. PMID: 36262394 Free PMC article.

2

CRBN ligand expansion for hematopoietic prostaglandin D₂ synthase (H-PGDS) targeting PROTAC design and their in vitro ADME profiles.

Osawa H, Kurohara T, Ito T, Shibata N, Demizu Y. Osawa H, et al. Among authors: kurohara t. Bioorg Med Chem. 2023 Apr 15;84:117259. doi: 10.1016/j.bmc.2023.117259. Epub 2023 Mar 30. Bioorg Med Chem. 2023. PMID: 37018877

3

N⁺-C-H···O Hydrogen bonds in protein-ligand complexes.

Itoh Y, Nakashima Y, Tsukamoto S, Kurohara T, Suzuki M, Sakae Y, Oda M, Okamoto Y, Suzuki T. Itoh Y, et al. Among authors: kurohara t. Sci Rep. 2019 Jan 25;9(1):767. doi: 10.1038/s41598-018-36987-9. Sci Rep. 2019. PMID: 30683882 Free PMC article.

4

Origin of the kinetic HDAC2-selectivity of an HDAC inhibitor.

Mishima H, Itoh Y, Kurohara T, Suzuki T, Asada N, Kusakabe KI, Okamoto Y. Mishima H, et al. Among authors: kurohara t. J Comput Chem. 2023 Jul 5;44(18):1604-1609. doi: 10.1002/jcc.27111. Epub 2023 Apr 19. J Comput Chem. 2023. PMID: 37074817

5

Discovery of novel tetrahydrobenzo[b]thiophene-3-carbonitriles as histone deacetylase inhibitors.

Gediya P, Vyas VK, Carafa V, Sitwala N, Della Torre L, Poziello A, Kurohara T, Suzuki T, Sanna V, Raguraman V, Suthindhiran K, Ghosh D, Bhatia D, Altucci L, Ghate MD. Gediya P, et al. Among authors: kurohara t. Bioorg Chem. 2021 May;110:104801. doi: 10.1016/j.bioorg.2021.104801. Epub 2021 Mar 5. Bioorg Chem. 2021. PMID: 33756235

6

Oligoarginine-Conjugated Peptide Foldamers Inhibiting Vitamin D Receptor-Mediated Transcription.

Takyo M, Sato Y, Hirata N, Tsuchiya K, Ishida H, Kurohara T, Yanase Y, Ito T, Kanda Y, Yamamoto K, Misawa T, Demizu Y. Takyo M, et al. Among authors: kurohara t. ACS Omega. 2022 Dec 12;7(50):46573-46582. doi: 10.1021/acsomega.2c05409. eCollection 2022 Dec 20. ACS Omega. 2022. PMID: 36570290 Free PMC article.

7

In silico optimization of peptides that inhibit Wnt/β-catenin signaling.

Fujita M, Tsuchiya K, Kurohara T, Fukuhara K, Misawa T, Demizu Y. Fujita M, et al. Among authors: kurohara t. Bioorg Med Chem. 2023 Apr 15;84:117264. doi: 10.1016/j.bmc.2023.117264. Epub 2023 Mar 25. Bioorg Med Chem. 2023. PMID: 37003158

8

Development of a penetratin-conjugated stapled peptide that inhibits Wnt/β-catenin signaling.

Tsuchiya K, Kiyoshi M, Hashii N, Fujita M, Kurohara T, Ishii-Watabe A, Fukuhara K, Misawa T, Demizu Y. Tsuchiya K, et al. Among authors: kurohara t. Bioorg Med Chem. 2022 Nov 1;73:117021. doi: 10.1016/j.bmc.2022.117021. Epub 2022 Sep 28. Bioorg Med Chem. 2022. PMID: 36198218

9

Structure-activity relationship study of PROTACs against hematopoietic prostaglandin D₂ synthase.

Murakami Y, Osawa H, Kurohara T, Yanase Y, Ito T, Yokoo H, Shibata N, Naito M, Aritake K, Demizu Y. Murakami Y, et al. Among authors: kurohara t. RSC Med Chem. 2022 Sep 23;13(12):1495-1503. doi: 10.1039/d2md00284a. eCollection 2022 Dec 14. RSC Med Chem. 2022. PMID: 36561070 Free PMC article.

10

Development of Rapid and Facile Solid-Phase Synthesis of PROTACs via a Variety of Binding Styles.

Xu H, Kurohara T, Takano R, Yokoo H, Shibata N, Ohoka N, Inoue T, Naito M, Demizu Y. Xu H, et al. Among authors: kurohara t. ChemistryOpen. 2022 Jul;11(7):e202200131. doi: 10.1002/open.202200131. ChemistryOpen. 2022. PMID: 35822913 Free PMC article.

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