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Highly potent, orally active novel small-molecule HPK1 inhibitor DS21150768 induces anti-tumor responses in multiple syngeneic tumor mouse models.
Setsu G, Goto M, Ito K, Taira T, Miyamoto M, Watanabe T, Taniguchi T, Umezaki Y, Nakazawa Y, Uesugi S, Mori K, Horiuchi T, Obuchi W, Minami M, Shimada T, Wada C, Yoshida T, Higuchi S. Setsu G, et al. Eur J Pharmacol. 2023 Dec 15;961:176184. doi: 10.1016/j.ejphar.2023.176184. Epub 2023 Nov 8. Eur J Pharmacol. 2023. PMID: 37944847
Efficacy of exogenous atrial natriuretic peptide in patients with heart failure with preserved ejection fraction: deficiency of atrial natriuretic peptide and replacement therapy.
Matsumoto S, Nakazawa G, Ohno Y, Ishihara M, Sakai K, Nakamura N, Murakami T, Natsumeda M, Kabuki T, Shibata A, Kida K, Konishi M, Ishii S, Ikeda T, Ikari Y. Matsumoto S, et al. ESC Heart Fail. 2020 Dec;7(6):4172-4181. doi: 10.1002/ehf2.13042. Epub 2020 Oct 10. ESC Heart Fail. 2020. PMID: 33037750 Free PMC article.