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Page 1
Metformin suppresses epithelial sodium channel hyperactivation and its associated phenotypes in a mouse model of obstructive lung diseases.
Nakashima R, Nohara H, Takahashi N, Nasu A, Hayashi M, Kishimoto T, Kamei S, Fujikawa H, Maruta K, Kawakami T, Eto Y, Ueno-Shuto K, Suico MA, Kai H, Shuto T. Nakashima R, et al. Among authors: kawakami t. J Pharmacol Sci. 2022 Jun;149(2):37-45. doi: 10.1016/j.jphs.2022.03.002. Epub 2022 Mar 23. J Pharmacol Sci. 2022. PMID: 35512853 Free article.
T3 Intratracheal Therapy Alleviates Pulmonary Pathology in an Elastase-Induced Emphysema-Dominant COPD Mouse Model.
Takahashi N, Nakashima R, Nasu A, Hayashi M, Fujikawa H, Kawakami T, Eto Y, Kishimoto T, Fukuyama A, Ogasawara C, Kawano K, Fujiwara Y, Suico MA, Kai H, Shuto T. Takahashi N, et al. Among authors: kawakami t. Antioxidants (Basel). 2023 Dec 22;13(1):30. doi: 10.3390/antiox13010030. Antioxidants (Basel). 2023. PMID: 38247455 Free PMC article.
Melinjo seed extract increases adiponectin multimerization in physiological and pathological conditions.
Oniki K, Kawakami T, Nakashima A, Miyata K, Watanabe T, Fujikawa H, Nakashima R, Nasu A, Eto Y, Takahashi N, Nohara H, Suico MA, Kotani S, Obata Y, Sakamoto Y, Seguchi Y, Saruwatari J, Imafuku T, Watanabe H, Maruyama T, Kai H, Shuto T. Oniki K, et al. Among authors: kawakami t. Sci Rep. 2020 Mar 9;10(1):4313. doi: 10.1038/s41598-020-61148-2. Sci Rep. 2020. PMID: 32152335 Free PMC article. Clinical Trial.
Integrative expression analysis identifies a novel interplay between CFTR and linc-SUMF1-2 that involves CF-associated gene dysregulation.
Kamei S, Maruta K, Fujikawa H, Nohara H, Ueno-Shuto K, Tasaki Y, Nakashima R, Kawakami T, Eto Y, Suico MA, Suzuki S, Gruenert DC, Li JD, Kai H, Shuto T. Kamei S, et al. Among authors: kawakami t. Biochem Biophys Res Commun. 2019 Feb 5;509(2):521-528. doi: 10.1016/j.bbrc.2018.12.152. Epub 2018 Dec 28. Biochem Biophys Res Commun. 2019. PMID: 30598261 Free article.
Intratracheal GLP-1 receptor agonist treatment up-regulates mucin via p38 and exacerbates emphysematous phenotype in mucus hypersecretory obstructive lung diseases.
Nohara H, Nakashima R, Kamei S, Fujikawa H, Ueno-Shuto K, Kawakami T, Eto Y, Suico MA, Li JD, Kai H, Shuto T. Nohara H, et al. Among authors: kawakami t. Biochem Biophys Res Commun. 2020 Apr 2;524(2):332-339. doi: 10.1016/j.bbrc.2020.01.081. Epub 2020 Jan 26. Biochem Biophys Res Commun. 2020. PMID: 31996306
Zinc Deficiency via a Splice Switch in Zinc Importer ZIP2/SLC39A2 Causes Cystic Fibrosis-Associated MUC5AC Hypersecretion in Airway Epithelial Cells.
Kamei S, Fujikawa H, Nohara H, Ueno-Shuto K, Maruta K, Nakashima R, Kawakami T, Matsumoto C, Sakaguchi Y, Ono T, Suico MA, Boucher RC, Gruenert DC, Takeo T, Nakagata N, Li JD, Kai H, Shuto T. Kamei S, et al. Among authors: kawakami t. EBioMedicine. 2018 Jan;27:304-316. doi: 10.1016/j.ebiom.2017.12.025. Epub 2017 Dec 20. EBioMedicine. 2018. PMID: 29289532 Free PMC article.
Auto-measure emphysematous parameters and pathophysiological gene expression profiles in experimental mouse models of acute and chronic obstructive pulmonary diseases.
Nakashima R, Kamei S, Nohara H, Fujikawa H, Maruta K, Kawakami T, Eto Y, Takahashi N, Suico MA, Takeo T, Nakagata N, Kai H, Shuto T. Nakashima R, et al. Among authors: kawakami t. J Pharmacol Sci. 2019 Jun;140(2):113-119. doi: 10.1016/j.jphs.2019.01.011. Epub 2019 Mar 26. J Pharmacol Sci. 2019. PMID: 31248767 Free article.
Pharmacological and genetic reappraisals of protease and oxidative stress pathways in a mouse model of obstructive lung diseases.
Shuto T, Kamei S, Nohara H, Fujikawa H, Tasaki Y, Sugahara T, Ono T, Matsumoto C, Sakaguchi Y, Maruta K, Nakashima R, Kawakami T, Suico MA, Kondo Y, Ishigami A, Takeo T, Tanaka KI, Watanabe H, Nakagata N, Uchimura K, Kitamura K, Li JD, Kai H. Shuto T, et al. Among authors: kawakami t. Sci Rep. 2016 Dec 16;6:39305. doi: 10.1038/srep39305. Sci Rep. 2016. PMID: 27982104 Free PMC article.
Higher Blood Uric Acid in Female Humans and Mice as a Protective Factor against Pathophysiological Decline of Lung Function.
Fujikawa H, Sakamoto Y, Masuda N, Oniki K, Kamei S, Nohara H, Nakashima R, Maruta K, Kawakami T, Eto Y, Takahashi N, Takeo T, Nakagata N, Watanabe H, Otake K, Ogata Y, Tomioka NH, Hosoyamada M, Takada T, Ueno-Shuto K, Suico MA, Kai H, Saruwatari J, Shuto T. Fujikawa H, et al. Among authors: kawakami t. Antioxidants (Basel). 2020 May 6;9(5):387. doi: 10.3390/antiox9050387. Antioxidants (Basel). 2020. PMID: 32384764 Free PMC article.