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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1974 1
1975 1
1976 4
1977 13
1978 9
1979 6
1980 15
1981 9
1982 19
1983 18
1984 20
1985 24
1986 28
1987 25
1988 40
1989 49
1990 65
1991 42
1992 64
1993 60
1994 60
1995 64
1996 72
1997 65
1998 69
1999 101
2000 97
2001 87
2002 72
2003 102
2004 104
2005 119
2006 94
2007 130
2008 119
2009 107
2010 140
2011 156
2012 191
2013 182
2014 193
2015 198
2016 116
2017 94
2018 144
2019 164
2020 144
2021 153
2022 163
2023 126
2024 26

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3,810 results

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Page 1
Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials.
Yang JC, Wu YL, Schuler M, Sebastian M, Popat S, Yamamoto N, Zhou C, Hu CP, O'Byrne K, Feng J, Lu S, Huang Y, Geater SL, Lee KY, Tsai CM, Gorbunova V, Hirsh V, Bennouna J, Orlov S, Mok T, Boyer M, Su WC, Lee KH, Kato T, Massey D, Shahidi M, Zazulina V, Sequist LV. Yang JC, et al. Lancet Oncol. 2015 Feb;16(2):141-51. doi: 10.1016/S1470-2045(14)71173-8. Epub 2015 Jan 12. Lancet Oncol. 2015. PMID: 25589191 Free article. Clinical Trial.
METHODS: Previously untreated patients with EGFR mutation-positive stage IIIB or IV lung adenocarcinoma were enrolled in LUX-Lung 3 (n=345) and LUX-Lung 6 (n=364). These patients were randomly assigned in a 2:1 ratio to receive afatinib or chemotherapy (pemetrexed-c …
METHODS: Previously untreated patients with EGFR mutation-positive stage IIIB or IV lung adenocarcinoma were enrolled in LUX-Lung 3 ( …
Secreting-lux/pT-ClyA engineered bacteria suppresses tumor growth via interleukin-1beta in two pathways.
Wu Y, Feng Z, Jiang S, Chen J, Zhan Y, Chen J. Wu Y, et al. AMB Express. 2019 Nov 21;9(1):189. doi: 10.1186/s13568-019-0910-6. AMB Express. 2019. PMID: 31754923 Free PMC article.
The CT26 tumor mouse model was used, and mice were treated in the following ways: PBS, S.t-deltapG(lux/pT-ClyA(+)) + IL-1betaAb, SL, S.t-deltapG(lux/pT-ClyA(-)), and S.t-deltapG(lux/pT-ClyA(+)). Dynamic evaluation of the efficacy of S. …
The CT26 tumor mouse model was used, and mice were treated in the following ways: PBS, S.t-deltapG(lux/pT-ClyA(+)) + IL-1betaA …
LUX ARRHYTHMO mediates crosstalk between the circadian clock and defense in Arabidopsis.
Zhang C, Gao M, Seitz NC, Angel W, Hallworth A, Wiratan L, Darwish O, Alkharouf N, Dawit T, Lin D, Egoshi R, Wang X, McClung CR, Lu H. Zhang C, et al. Nat Commun. 2019 Jun 11;10(1):2543. doi: 10.1038/s41467-019-10485-6. Nat Commun. 2019. PMID: 31186426 Free PMC article.
RNA-seq analysis reveals that both clock- and defense-related genes are regulated by LUX. LUX binds to clock gene promoters that have not been shown before, expanding the clock gene networks that require LUX function. LUX also binds to the promoters of …
RNA-seq analysis reveals that both clock- and defense-related genes are regulated by LUX. LUX binds to clock gene promoters th …
The evolution of the bacterial luciferase gene cassette (lux) as a real-time bioreporter.
Close D, Xu T, Smartt A, Rogers A, Crossley R, Price S, Ripp S, Sayler G. Close D, et al. Sensors (Basel). 2012;12(1):732-52. doi: 10.3390/s120100732. Epub 2012 Jan 11. Sensors (Basel). 2012. PMID: 22368493 Free PMC article. Review.
Under these conditions, the lux system has been developed for use as a biomedical detection tool for toxicity screening and visualization of tumors in small animal models. ...This review presents the basic biochemical background that allows the lux system to continu …
Under these conditions, the lux system has been developed for use as a biomedical detection tool for toxicity screening and visualiza …
Bacterial bioluminescence: organization, regulation, and application of the lux genes.
Meighen EA. Meighen EA. FASEB J. 1993 Aug;7(11):1016-22. doi: 10.1096/fasebj.7.11.8370470. FASEB J. 1993. PMID: 8370470 Review.
Significant advances have been made in the characterization of luciferases and other lux-specific proteins as well as the lux genes from a number of different species of marine and terrestrial luminescent bacteria. ...Identification of the lux autoinducers an …
Significant advances have been made in the characterization of luciferases and other lux-specific proteins as well as the lux …
Sulfanilamide Regulates Flowering Time through Expression of the Circadian Clock Gene LUX.
Hirohata A, Yamatsuta Y, Ogawa K, Kubota A, Suzuki T, Shimizu H, Kanesaka Y, Takahashi N, Endo M. Hirohata A, et al. Plant Cell Physiol. 2022 May 16;63(5):649-657. doi: 10.1093/pcp/pcac027. Plant Cell Physiol. 2022. PMID: 35238923
Here, we report that sulfanilamide, an inhibitor of folate biosynthesis, delays flowering by repressing the expression of florigen FLOWERING LOCUS T (FT) in Arabidopsis thaliana. Transcriptome deep sequencing and quantitative polymerase chain reaction analyses showed that …
Here, we report that sulfanilamide, an inhibitor of folate biosynthesis, delays flowering by repressing the expression of florigen FLOWERING …
Molecular biology of bacterial bioluminescence.
Meighen EA. Meighen EA. Microbiol Rev. 1991 Mar;55(1):123-42. doi: 10.1128/mr.55.1.123-142.1991. Microbiol Rev. 1991. PMID: 2030669 Free PMC article. Review.
All lux operons have a common gene organization of luxCDAB(F)E, with luxAB coding for luciferase and luxCDE coding for the fatty acid reductase complex responsible for synthesizing fatty aldehydes for the luminescence reaction, whereas significant differences exist in thei …
All lux operons have a common gene organization of luxCDAB(F)E, with luxAB coding for luciferase and luxCDE coding for the fatty acid …
Reliability analysis using the in-lux examination method for dental indices in adolescents for use in epidemiological studies.
Pinto RDS, Vettore MV, de Abreu MHGN, Palmier AC, de Moura RNV, Roncalli AG. Pinto RDS, et al. Community Dent Oral Epidemiol. 2023 Oct;51(5):847-853. doi: 10.1111/cdoe.12775. Epub 2022 Jul 21. Community Dent Oral Epidemiol. 2023. PMID: 35864597
OBJECTIVE: To evaluate the in-lux examination method to assess the reliability of examiners for oral health surveys. ...The first group carried out in vivo (clinical) and in-lux examinations in the same patients. The second group performed in-lux examinations …
OBJECTIVE: To evaluate the in-lux examination method to assess the reliability of examiners for oral health surveys. ...The first gro …
Bacterial Luciferase Gene Cassette as a Real-time Bioreporter for Infection Model and Drug Evaluation.
Wang X, Chi H, Zhou B, Li W, Li Z, Xia Z. Wang X, et al. Curr Pharm Des. 2018;24(8):952-958. doi: 10.2174/1381612824666180213121724. Curr Pharm Des. 2018. PMID: 29436995 Review.
The bacterial luciferase gene cassette (lux) is an ideal bioreporter for real-time monitoring of the dynamics of bacteria because it is a fully autonomous, substrate-free bioluminescent reporter system available in a prokaryotic or eukaryotic host background. ...Different …
The bacterial luciferase gene cassette (lux) is an ideal bioreporter for real-time monitoring of the dynamics of bacteria because it …
The LUX Score: A Metric for Lipidome Homology.
Marella C, Torda AE, Schwudke D. Marella C, et al. PLoS Comput Biol. 2015 Sep 22;11(9):e1004511. doi: 10.1371/journal.pcbi.1004511. eCollection 2015. PLoS Comput Biol. 2015. PMID: 26393792 Free PMC article.
We show that the LUX score reflects the genetic relationship and growth temperature better than conventional methods although the score is based solely on lipid structures. ...This study is the first effort to define a lipidome homology metric based on structures that will …
We show that the LUX score reflects the genetic relationship and growth temperature better than conventional methods although the sco …
3,810 results