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Year Number of Results
2013 1
2014 2
2015 2
2016 3
2017 6
2019 1
2020 3
2021 4
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2023 1
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Page 1
Recommendations on dose level selection for repeat dose toxicity studies.
Sewell F, Corvaro M, Andrus A, Burke J, Daston G, Delaney B, Domoradzki J, Forlini C, Green ML, Hofmann T, Jäckel S, Lee MS, Temerowski M, Whalley P, Lewis R. Sewell F, et al. Among authors: jackel s. Arch Toxicol. 2022 Jul;96(7):1921-1934. doi: 10.1007/s00204-022-03293-3. Epub 2022 Apr 29. Arch Toxicol. 2022. PMID: 35486138 Free PMC article. Review.
Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells.
Schaupp L, Muth S, Rogell L, Kofoed-Branzk M, Melchior F, Lienenklaus S, Ganal-Vonarburg SC, Klein M, Guendel F, Hain T, Schütze K, Grundmann U, Schmitt V, Dorsch M, Spanier J, Larsen PK, Schwanz T, Jäckel S, Reinhardt C, Bopp T, Danckwardt S, Mahnke K, Heinz GA, Mashreghi MF, Durek P, Kalinke U, Kretz O, Huber TB, Weiss S, Wilhelm C, Macpherson AJ, Schild H, Diefenbach A, Probst HC. Schaupp L, et al. Among authors: jackel s. Cell. 2020 May 28;181(5):1080-1096.e19. doi: 10.1016/j.cell.2020.04.022. Epub 2020 May 6. Cell. 2020. PMID: 32380006 Free article.
The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice.
Kiouptsi K, Jäckel S, Pontarollo G, Grill A, Kuijpers MJE, Wilms E, Weber C, Sommer F, Nagy M, Neideck C, Jansen Y, Ascher S, Formes H, Karwot C, Bayer F, Kollar B, Subramaniam S, Molitor M, Wenzel P, Rosenstiel P, Todorov H, Gerber S, Walter U, Jurk K, Heemskerk JWM, van der Vorst EPC, Döring Y, Reinhardt C. Kiouptsi K, et al. Among authors: jackel s. mBio. 2019 Oct 22;10(5):e02298-19. doi: 10.1128/mBio.02298-19. mBio. 2019. PMID: 31641089 Free PMC article.
Characterization of the immune system of Ellegaard Göttingen Minipigs - An important large animal model in experimental medicine.
Pernold CPS, Lagumdzic E, Stadler M, Mair KH, Jäckel S, Schmitt MW, Ladinig A, Knecht C, Dürlinger S, Kreutzmann H, Martin V, Sawyer S, Saalmüller A. Pernold CPS, et al. Among authors: jackel s. Front Immunol. 2022 Sep 20;13:1003986. doi: 10.3389/fimmu.2022.1003986. eCollection 2022. Front Immunol. 2022. PMID: 36203585 Free PMC article.
Species selection for nonclinical safety assessment of drug candidates: Examples of current industry practice.
Namdari R, Jones K, Chuang SS, Van Cruchten S, Dincer Z, Downes N, Mikkelsen LF, Harding J, Jäckel S, Jacobsen B, Kinyamu-Akunda J, Lortie A, Mhedhbi S, Mohr S, Schmitt MW, Prior H. Namdari R, et al. Among authors: jackel s. Regul Toxicol Pharmacol. 2021 Nov;126:105029. doi: 10.1016/j.yrtph.2021.105029. Epub 2021 Aug 27. Regul Toxicol Pharmacol. 2021. PMID: 34455009 Free article.
Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension.
Kossmann S, Lagrange J, Jäckel S, Jurk K, Ehlken M, Schönfelder T, Weihert Y, Knorr M, Brandt M, Xia N, Li H, Daiber A, Oelze M, Reinhardt C, Lackner K, Gruber A, Monia B, Karbach SH, Walter U, Ruggeri ZM, Renné T, Ruf W, Münzel T, Wenzel P. Kossmann S, et al. Among authors: jackel s. Sci Transl Med. 2017 Feb 1;9(375):eaah4923. doi: 10.1126/scitranslmed.aah4923. Sci Transl Med. 2017. PMID: 28148841
Discovery of 5-{2-[5-Chloro-2-(5-ethoxyquinoline-8-sulfonamido)phenyl]ethynyl}-4-methoxypyridine-2-carboxylic Acid, a Highly Selective in Vivo Useable Chemical Probe to Dissect MCT4 Biology.
Heinrich T, Sala-Hojman A, Ferretti R, Petersson C, Minguzzi S, Gondela A, Ramaswamy S, Bartosik A, Czauderna F, Crowley L, Wahra P, Schilke H, Böpple P, Dudek Ł, Leś M, Niedziejko P, Olech K, Pawlik H, Włoszczak Ł, Zuchowicz K, Suarez Alvarez JR, Martyka J, Sitek E, Mikulski M, Szczęśniak J, Jäckel S, Krier M, Król M, Wegener A, Gałęzowski M, Nowak M, Becker F, Herhaus C. Heinrich T, et al. Among authors: jackel s. J Med Chem. 2021 Aug 26;64(16):11904-11933. doi: 10.1021/acs.jmedchem.1c00448. Epub 2021 Aug 12. J Med Chem. 2021. PMID: 34382802
Gut Microbiota Promote Angiotensin II-Induced Arterial Hypertension and Vascular Dysfunction.
Karbach SH, Schönfelder T, Brandão I, Wilms E, Hörmann N, Jäckel S, Schüler R, Finger S, Knorr M, Lagrange J, Brandt M, Waisman A, Kossmann S, Schäfer K, Münzel T, Reinhardt C, Wenzel P. Karbach SH, et al. Among authors: jackel s. J Am Heart Assoc. 2016 Aug 30;5(9):e003698. doi: 10.1161/JAHA.116.003698. J Am Heart Assoc. 2016. PMID: 27577581 Free PMC article.
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