Modeling and implementation of voltage-mode CMOS dendrites on a reconfigurable analog platform

IEEE Trans Biomed Circuits Syst. 2012 Feb;6(1):76-84. doi: 10.1109/TBCAS.2011.2163714.

Abstract

Many decades ago, Wilfrid Rall and others laid the foundations for mathematical modeling of dendrites using cable theory. With reconfigurable analog architectures, we are now able to accurately program different circuit architectures to emulate dendrites. Our work has shown that these circuits accurately reproduce results predicted from cable theory when inputs to the system are small. For large inputs, interesting nonlinear effects begin to take hold.

MeSH terms

  • Dendrites / physiology*
  • Humans
  • Ion Channels / physiology
  • Models, Neurological*
  • Neural Networks, Computer*
  • Nonlinear Dynamics

Substances

  • Ion Channels