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Page 1
Showing results for stefan manner
Search for Stefan Menner instead (1 results)
Different Effects of Cannabis Abuse on Adolescent and Adult Brain.
Dhein S. Dhein S. Pharmacology. 2020;105(11-12):609-617. doi: 10.1159/000509377. Epub 2020 Jul 6. Pharmacology. 2020. PMID: 32629444 Free article. Review.
Since these factors play an important role in the brain development and in the neuronal conversion processes during puberty, it seems reasonable that THC can affect the adolescent brain in another manner than the adult brain. Accordingly, in adolescent cannabis users struc …
Since these factors play an important role in the brain development and in the neuronal conversion processes during puberty, it seems reason …
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
Prentzell MT, Rehbein U, Cadena Sandoval M, De Meulemeester AS, Baumeister R, Brohée L, Berdel B, Bockwoldt M, Carroll B, Chowdhury SR, von Deimling A, Demetriades C, Figlia G; Genomics England Research Consortium; de Araujo MEG, Heberle AM, Heiland I, Holzwarth B, Huber LA, Jaworski J, Kedra M, Kern K, Kopach A, Korolchuk VI, van 't Land-Kuper I, Macias M, Nellist M, Palm W, Pusch S, Ramos Pittol JM, Reil M, Reintjes A, Reuter F, Sampson JR, Scheldeman C, Siekierska A, Stefan E, Teleman AA, Thomas LE, Torres-Quesada O, Trump S, West HD, de Witte P, Woltering S, Yordanov TE, Zmorzynska J, Opitz CA, Thedieck K. Prentzell MT, et al. Cell. 2021 Feb 4;184(3):655-674.e27. doi: 10.1016/j.cell.2020.12.024. Epub 2021 Jan 25. Cell. 2021. PMID: 33497611 Free PMC article.
We report that G3BPs reside at the cytoplasmic surface of lysosomes. They act in a non-redundant manner to anchor the tuberous sclerosis complex (TSC) protein complex to lysosomes and suppress activation of the metabolic master regulator mechanistic target of rapamycin com …
We report that G3BPs reside at the cytoplasmic surface of lysosomes. They act in a non-redundant manner to anchor the tuberous sclero …
Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling.
Corsello SM, Nagari RT, Spangler RD, Rossen J, Kocak M, Bryan JG, Humeidi R, Peck D, Wu X, Tang AA, Wang VM, Bender SA, Lemire E, Narayan R, Montgomery P, Ben-David U, Garvie CW, Chen Y, Rees MG, Lyons NJ, McFarland JM, Wong BT, Wang L, Dumont N, O'Hearn PJ, Stefan E, Doench JG, Harrington CN, Greulich H, Meyerson M, Vazquez F, Subramanian A, Roth JA, Bittker JA, Boehm JS, Mader CC, Tsherniak A, Golub TR. Corsello SM, et al. Nat Cancer. 2020 Feb;1(2):235-248. doi: 10.1038/s43018-019-0018-6. Epub 2020 Jan 20. Nat Cancer. 2020. PMID: 32613204 Free PMC article.
An unexpectedly large number of non-oncology drugs selectively inhibited subsets of cancer cell lines in a manner predictable from the cell lines' molecular features. Our findings include compounds that killed by inducing PDE3A-SLFN12 complex formation; vanadium-containing …
An unexpectedly large number of non-oncology drugs selectively inhibited subsets of cancer cell lines in a manner predictable from th …
Heme Oxygenase-1: An Anti-Inflammatory Effector in Cardiovascular, Lung, and Related Metabolic Disorders.
Ryter SW. Ryter SW. Antioxidants (Basel). 2022 Mar 15;11(3):555. doi: 10.3390/antiox11030555. Antioxidants (Basel). 2022. PMID: 35326205 Free PMC article. Review.
The expression of HO-1 is regulated by NF-E2-related factor-2 and counter-regulated by Bach-1, in a heme-sensitive manner. Additionally, HMOX1 promoter polymorphisms have been associated with human disease. ...
The expression of HO-1 is regulated by NF-E2-related factor-2 and counter-regulated by Bach-1, in a heme-sensitive manner. Additional …
Incidence of severe critical events in paediatric anaesthesia (APRICOT): a prospective multicentre observational study in 261 hospitals in Europe.
Habre W, Disma N, Virag K, Becke K, Hansen TG, Jöhr M, Leva B, Morton NS, Vermeulen PM, Zielinska M, Boda K, Veyckemans F; APRICOT Group of the European Society of Anaesthesiology Clinical Trial Network. Habre W, et al. Lancet Respir Med. 2017 May;5(5):412-425. doi: 10.1016/S2213-2600(17)30116-9. Epub 2017 Mar 28. Lancet Respir Med. 2017. PMID: 28363725
[Acute abdominal trauma].
Gäble A, Mück F, Mühlmann M, Wirth S. Gäble A, et al. Radiologe. 2019 Feb;59(2):139-145. doi: 10.1007/s00117-018-0485-2. Radiologe. 2019. PMID: 30627752 Review. German.
BACKGROUND: In patients with multiple trauma, abdominal involvement is a particularly relevant injury pattern. Depending on the intensity and manner of injury, heterogeneous but often typical organ manifestations result. ...
BACKGROUND: In patients with multiple trauma, abdominal involvement is a particularly relevant injury pattern. Depending on the intensity an …
The substrate repertoire of γ-secretase/presenilin.
Güner G, Lichtenthaler SF. Güner G, et al. Semin Cell Dev Biol. 2020 Sep;105:27-42. doi: 10.1016/j.semcdb.2020.05.019. Epub 2020 Jun 29. Semin Cell Dev Biol. 2020. PMID: 32616437 Review.
Taken together, the list of substrates provides a resource that may help in the future development of drugs inhibiting or modulating gamma-secretase activity in a substrate-specific manner....
Taken together, the list of substrates provides a resource that may help in the future development of drugs inhibiting or modulating gamma-s …
Neuroradiological and clinical features in ophthalmoplegia.
Weidauer S, Hofmann C, Wagner M, Hattingen E. Weidauer S, et al. Neuroradiology. 2019 Apr;61(4):365-387. doi: 10.1007/s00234-019-02183-3. Epub 2019 Feb 12. Neuroradiology. 2019. PMID: 30747268 Review.
RESULTS: To present those ophthalmoplegic disorders in a clear manner, this review refers to different neuroanatomical structures and compartments. ...
RESULTS: To present those ophthalmoplegic disorders in a clear manner, this review refers to different neuroanatomical structures and …
397 results