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Showing results for stefan caco
Your search for Stefan Cacoń retrieved no results
Assessment of the potential of the MET inhibitor tepotinib to affect the pharmacokinetics of CYP3A4 and P-gp substrates.
Yalkinoglu Ö, Becker A, Krebs-Brown A, Vetter C, Lüpfert C, Perrin D, Heuer J, Biedert H, Hirt S, Bytyqi A, Bachmann A, Strotmann R. Yalkinoglu Ö, et al. Invest New Drugs. 2023 Aug;41(4):596-605. doi: 10.1007/s10637-023-01378-z. Epub 2023 Jul 6. Invest New Drugs. 2023. PMID: 37415001 Free PMC article.
In vitro studies were conducted in human liver microsomes, human hepatocyte cultures and Caco-2 cell monolayers to investigate whether tepotinib or its major metabolite (MSC2571109A) inhibited or induced CYP3A4/5 or inhibited P-gp. ...
In vitro studies were conducted in human liver microsomes, human hepatocyte cultures and Caco-2 cell monolayers to investigate whethe …
Anti-Proliferative Potential of Cynaroside and Orientin-In Silico (DYRK2) and In Vitro (U87 and Caco-2) Studies.
Pirvu LC, Pintilie L, Albulescu A, Stefaniu A, Neagu G. Pirvu LC, et al. Int J Mol Sci. 2023 Nov 21;24(23):16555. doi: 10.3390/ijms242316555. Int J Mol Sci. 2023. PMID: 38068880 Free PMC article.
In vitro studies were performed on two human tumor cell lines, glioblastoma (U87) and colon carcinoma (Caco-2), respectively. Altogether, docking studies have revealed 7-Lut and 8-Lut as effective inhibitors of DYRK2, even stronger than the native ligand curcumin; in vitro …
In vitro studies were performed on two human tumor cell lines, glioblastoma (U87) and colon carcinoma (Caco-2), respectively. Altoget …
Lectin-Mediated Binding of Engineered Lactococcus lactis to Cancer Cells.
Plavec TV, Zahirović A, Zadravec P, Sabotič J, Berlec A. Plavec TV, et al. Microorganisms. 2021 Jan 22;9(2):223. doi: 10.3390/microorganisms9020223. Microorganisms. 2021. PMID: 33499141 Free PMC article.
Stx1B bound to Caco-2, HT-29 and HeLa cells after 1 h of incubation. CNL bound to Caco-2 cells and recognized several glycoproteins in HT-29 and Caco-2 cell homogenates of which a 70 kDa protein predominated. Confocal microscopy revealed adhesion of Stx1B-dis …
Stx1B bound to Caco-2, HT-29 and HeLa cells after 1 h of incubation. CNL bound to Caco-2 cells and recognized several glycopro …
In Vitro Studies Demonstrate Antitumor Activity of Vanadium Ions from a CaO-P(2)O(5)-CaF(2):V(2)O(5) Glass System in Human Cancer Cell Lines A375, A2780, and Caco-2.
Lujerdean C, Zăhan M, Dezmirean DS, Ștefan R, Simedru D, Damian G, Vedeanu NS. Lujerdean C, et al. Int J Mol Sci. 2023 Jan 6;24(2):1149. doi: 10.3390/ijms24021149. Int J Mol Sci. 2023. PMID: 36674660 Free PMC article.
In vitro tests were conducted to assess the antitumor character of V2O5-doped glass (x = 16 mol%) compared to the matrix (x = 0 mol%) and control (CTRL-) using several tumoral cell lines (A375, A2780, and Caco-2). The characterization of PGs showed an overall dissolution r …
In vitro tests were conducted to assess the antitumor character of V2O5-doped glass (x = 16 mol%) compared to the matrix (x = 0 mol%) and co …
Evaluation of angularly condensed diquinothiazines as potential anticancer agents.
Jeleń M, Pluta K, Latocha M, Morak-Młodawska B, Suwińska K, Kuśmierz D. Jeleń M, et al. Bioorg Chem. 2019 Jun;87:810-820. doi: 10.1016/j.bioorg.2019.04.005. Epub 2019 Apr 6. Bioorg Chem. 2019. PMID: 30981160

Most of diquinothiazines exhibited significant cancer cell growth inhibition against the human glioblastoma SNB-19, colorectal carcinoma Caco-2, breast cancer MDA-MB-231 and lung cancer A549 cell lines with the IC(50) values < 3 M. ...The expression of H3, TP53, CDKN1A,

…
Most of diquinothiazines exhibited significant cancer cell growth inhibition against the human glioblastoma SNB-19, colorectal carcinoma …
The Organic Anion-Transporting Peptide 2B1 Is Localized in the Basolateral Membrane of the Human Jejunum and Caco-2 Monolayers.
Keiser M, Kaltheuner L, Wildberg C, Müller J, Grube M, Partecke LI, Heidecke CD, Oswald S. Keiser M, et al. J Pharm Sci. 2017 Sep;106(9):2657-2663. doi: 10.1016/j.xphs.2017.04.001. Epub 2017 Apr 10. J Pharm Sci. 2017. PMID: 28408210
Thus, it was the aim of this study to investigate its localization and function in the human jejunum and in the frequently used intestinal Caco-2 cell line. The basolateral membrane of jejunal tissue from 6 individuals showed a significant enrichment of OATP2B1 (17-fold) a …
Thus, it was the aim of this study to investigate its localization and function in the human jejunum and in the frequently used intestinal …
Evasin-displaying lactic acid bacteria bind different chemokines and neutralize CXCL8 production in Caco-2 cells.
Škrlec K, Pucer Janež A, Rogelj B, Štrukelj B, Berlec A. Škrlec K, et al. Microb Biotechnol. 2017 Nov;10(6):1732-1743. doi: 10.1111/1751-7915.12781. Epub 2017 Jul 24. Microb Biotechnol. 2017. PMID: 28736998 Free PMC article.
Evasin-3-displaying L. lactis removed 76.0% of IL-1beta-induced CXCL8 from the supernatant of Caco-2 epithelial cells. It also prevented secretion of CXCL8 from Caco-2 cells in a time-dependent manner when added before induction with IL-1beta. ...
Evasin-3-displaying L. lactis removed 76.0% of IL-1beta-induced CXCL8 from the supernatant of Caco-2 epithelial cells. It also preven …
Dual Functionalized Lactococcus lactis Shows Tumor Antigen Targeting and Cytokine Binding in Vitro.
Zahirović A, Plavec TV, Berlec A. Zahirović A, et al. Front Bioeng Biotechnol. 2022 Jan 26;10:822823. doi: 10.3389/fbioe.2022.822823. eCollection 2022. Front Bioeng Biotechnol. 2022. PMID: 35155394 Free PMC article.
To assess the removal of IL-8 and IL-6 by the engineered bacteria, we established inflammatory cell models by stimulating cytokine secretion in human colon adenocarcinoma cells (Caco-2; HT-29) and monocyte-like cells (THP-1; U-937). The engineered L. lactis removed conside …
To assess the removal of IL-8 and IL-6 by the engineered bacteria, we established inflammatory cell models by stimulating cytokine secretion …
The effects of hydrothermal processing and germination on Fe speciation and Fe bioaccessibility to human intestinal Caco-2 cells in Tartary buckwheat.
Pongrac P, Scheers N, Sandberg AS, Potisek M, Arčon I, Kreft I, Kump P, Vogel-Mikuš K. Pongrac P, et al. Food Chem. 2016 May 15;199:782-90. doi: 10.1016/j.foodchem.2015.12.071. Epub 2015 Dec 18. Food Chem. 2016. PMID: 26776035
The aim of the study was to investigate how processing of grains into groats (hydrothermal processing to remove the husk) and sprouts (7-day-old seedlings) affected Fe speciation (Fe(2+) or Fe(3+)), Fe ligand composition and Fe bioaccessibility to human Caco-2 cells. Groat …
The aim of the study was to investigate how processing of grains into groats (hydrothermal processing to remove the husk) and sprouts (7-day …
33 results