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1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(meth-yl)amino]-piperidin-1-yl}propan-1-one.
IUCrdata. 2021 Feb 23;6(Pt 2):x210159. doi: 10.1107/S2414314621001590. eCollection 2021 Feb.
IUCrdata. 2021.
PMID: 36338864
Free PMC article.
Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors.
Andreev S, Pantsar T, Tesch R, Kahlke N, El-Gokha A, Ansideri F, Grätz L, Romasco J, Sita G, Geibel C, Lämmerhofer M, Tarozzi A, Knapp S, Laufer SA, Koch P.
Andreev S, et al.
J Med Chem. 2022 Jan 27;65(2):1283-1301. doi: 10.1021/acs.jmedchem.0c02146. Epub 2021 Jul 2.
J Med Chem. 2022.
PMID: 34213342
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Photocaging of Pyridinylimidazole-Based Covalent JNK3 Inhibitors Affords Spatiotemporal Control of the Binding Affinity in Live Cells.
Hoffelner BS, Andreev S, Plank N, Koch P.
Hoffelner BS, et al. Among authors: andreev s.
Pharmaceuticals (Basel). 2023 Feb 9;16(2):264. doi: 10.3390/ph16020264.
Pharmaceuticals (Basel). 2023.
PMID: 37259409
Free PMC article.
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Design, Synthesis and Biological Evaluation of 7-Chloro-9H-pyrimido[4,5-b]indole-based Glycogen Synthase Kinase-3β Inhibitors.
Andreev S, Pantsar T, Ansideri F, Kudolo M, Forster M, Schollmeyer D, Laufer SA, Koch P.
Andreev S, et al.
Molecules. 2019 Jun 25;24(12):2331. doi: 10.3390/molecules24122331.
Molecules. 2019.
PMID: 31242571
Free PMC article.
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Discovery and Evaluation of Enantiopure 9H-pyrimido[4,5-b]indoles as Nanomolar GSK-3β Inhibitors with Improved Metabolic Stability.
Andreev S, Pantsar T, El-Gokha A, Ansideri F, Kudolo M, Anton DB, Sita G, Romasco J, Geibel C, Lämmerhofer M, Goettert MI, Tarozzi A, Laufer SA, Koch P.
Andreev S, et al.
Int J Mol Sci. 2020 Oct 22;21(21):7823. doi: 10.3390/ijms21217823.
Int J Mol Sci. 2020.
PMID: 33105671
Free PMC article.
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A Diverse and Versatile Regiospecific Synthesis of Tetrasubstituted Alkylsulfanylimidazoles as p38α Mitogen-Activated Protein Kinase Inhibitors.
Ansideri F, Andreev S, Kuhn A, Albrecht W, Laufer SA, Koch P.
Ansideri F, et al. Among authors: andreev s.
Molecules. 2018 Jan 20;23(1):221. doi: 10.3390/molecules23010221.
Molecules. 2018.
PMID: 29361698
Free PMC article.
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