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Page 1
STEEP mediates STING ER exit and activation of signaling.
Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R, Hartmann R, Chen ZJ, Enghild JJ, Bak RO, Thomsen MK, Paludan SR. Zhang BC, et al. Among authors: assil s. Nat Immunol. 2020 Aug;21(8):868-879. doi: 10.1038/s41590-020-0730-5. Epub 2020 Jul 20. Nat Immunol. 2020. PMID: 32690950 Free PMC article.
STING is ESCRTed to degradation by microautophagy.
Assil S, Paludan SR. Assil S, et al. Nat Cell Biol. 2023 Mar;25(3):379-380. doi: 10.1038/s41556-022-01084-7. Nat Cell Biol. 2023. PMID: 36918691 No abstract available.
SAM68 directs STING signaling to apoptosis in macrophages.
van der Horst D, Kurmasheva N, Marqvorsen MHS, Assil S, Rahimic AHF, Kollmann CF, Silva da Costa L, Wu Q, Zhao J, Cesari E, Iversen MB, Ren F, Jensen TI, Narita R, Schack VR, Zhang BC, Bak RO, Sette C, Fenton RA, Mikkelsen JG, Paludan SR, Olagnier D. van der Horst D, et al. Among authors: assil s. Commun Biol. 2024 Mar 7;7(1):283. doi: 10.1038/s42003-024-05969-1. Commun Biol. 2024. PMID: 38454028 Free PMC article.
Intracellular bacteria engage a STING-TBK1-MVB12b pathway to enable paracrine cGAS-STING signalling.
Nandakumar R, Tschismarov R, Meissner F, Prabakaran T, Krissanaprasit A, Farahani E, Zhang BC, Assil S, Martin A, Bertrams W, Holm CK, Ablasser A, Klause T, Thomsen MK, Schmeck B, Howard KA, Henry T, Gothelf KV, Decker T, Paludan SR. Nandakumar R, et al. Among authors: assil s. Nat Microbiol. 2019 Apr;4(4):701-713. doi: 10.1038/s41564-019-0367-z. Epub 2019 Feb 25. Nat Microbiol. 2019. PMID: 30804548 Free PMC article.
20 results