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Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity.
Haematologica. 2023 Sep 1;108(9):2343-2357. doi: 10.3324/haematol.2022.281894.
Haematologica. 2023.
PMID: 37021547
Free PMC article.
In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target.
Vujovic A, de Rooij L, Chahi AK, Chen HT, Yee BA, Loganathan SK, Liu L, Chan DCH, Tajik A, Tsao E, Moreira S, Joshi P, Xu J, Wong N, Balde Z, Jahangiri S, Zandi S, Aigner S, Dick JE, Minden MD, Schramek D, Yeo GW, Hope KJ.
Vujovic A, et al. Among authors: jahangiri s.
Blood Cancer Discov. 2023 May 1;4(3):180-207. doi: 10.1158/2643-3230.BCD-22-0086.
Blood Cancer Discov. 2023.
PMID: 36763002
Free PMC article.
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