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The WNK1-ERK5 route plays a pathophysiological role in ovarian cancer and limits therapeutic efficacy of trametinib.
Sánchez-Fdez A, Matilla-Almazán S, Montero JC, Del Carmen S, Abad M, García-Alonso S, Bhattacharya S, Calar K, de la Puente P, Ocaña A, Pandiella A, Esparís-Ogando A. Sánchez-Fdez A, et al. Among authors: matilla almazan s. Clin Transl Med. 2023 Apr;13(4):e1217. doi: 10.1002/ctm2.1217. Clin Transl Med. 2023. PMID: 37029785 Free PMC article.
Etiopathogenic role of ERK5 signaling in sarcoma: prognostic and therapeutic implications.
Sánchez-Fdez A, Matilla-Almazán S, Del Carmen S, Abad M, Arconada-Luque E, Jiménez-Suárez J, Chinchilla-Tábora LM, Ruíz-Hidalgo MJ, Sánchez-Prieto R, Pandiella A, Esparís-Ogando A. Sánchez-Fdez A, et al. Among authors: matilla almazan s. Exp Mol Med. 2023 Jun;55(6):1247-1257. doi: 10.1038/s12276-023-01008-x. Epub 2023 Jun 19. Exp Mol Med. 2023. PMID: 37332046 Free PMC article.
ERK5 Is a Major Determinant of Chemical Sarcomagenesis: Implications in Human Pathology.
Arconada-Luque E, Jiménez-Suarez J, Pascual-Serra R, Nam-Cha SH, Moline T, Cimas FJ, Fliquete G, Ortega-Muelas M, Roche O, Fernández-Aroca DM, Muñoz Velasco R, García-Flores N, Garnés-García C, Sánchez-Fdez A, Matilla-Almazán S, Sánchez-Arévalo Lobo VJ, Hernández-Losa J, Belandia B, Pandiella A, Esparís-Ogando A, Ramón Y Cajal S, Del Peso L, Sánchez-Prieto R, Ruiz-Hidalgo MJ. Arconada-Luque E, et al. Among authors: matilla almazan s. Cancers (Basel). 2022 Jul 19;14(14):3509. doi: 10.3390/cancers14143509. Cancers (Basel). 2022. PMID: 35884568 Free PMC article.