Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves

Mohd Azrie Awang; Mohammad Amil Zulhilmi Benjamin; Adilah Anuar; Mohd Fakhrulddin Ismail; Shiamala Devi Ramaiya; Siti Nur Aisyah Mohd Hashim

doi:10.1016/j.dib.2023.109644

Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves

Data Brief. 2023 Oct 5:51:109644. doi: 10.1016/j.dib.2023.109644. eCollection 2023 Dec.

Authors

Mohd Azrie Awang^{1

2}, Mohammad Amil Zulhilmi Benjamin³, Adilah Anuar⁴, Mohd Fakhrulddin Ismail⁵, Shiamala Devi Ramaiya⁶, Siti Nur Aisyah Mohd Hashim⁷

Affiliations

¹ Faculty of Food Science and Nutrition, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, Malaysia.
² Innovative Food Processing and Ingredient Research Group, Faculty of Food Science and Nutrition, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, Malaysia.
³ Borneo Research on Algesia, Inflammation and Neurodegeneration (BRAIN) Group, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, Malaysia.
⁴ Faculty of Chemical Engineering and Technology, Universiti Malaysia Perlis, Kampus UniCITI Alam, Sungai Chuchuh, 02100 Padang Besar, Perlis, Malaysia.
⁵ International Institute of Aquaculture and Aquatic Sciences (I-AQUAS), Universiti Putra Malaysia, Lot 960 Jln Kemang 6, 71050 Port Dickson, Negeri Sembilan, Malaysia.
⁶ Department of Crop Science, Faculty of Agricultural and Forestry Sciences, Universiti Putra Malaysia Kampus Bintulu Sarawak, Jalan Nyabau, 97008 Bintulu, Sarawak, Malaysia.
⁷ Bioactivity Programme, Natural Products Division, Forest Research Institute Malaysia (FRIM), 52109 Kepong, Selangor Darul Ehsan, Malaysia.

Abstract

The article presents data on the quantification of gallic acid (GA) and the assessment of the antioxidant and anti-inflammatory properties of Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves using various solvents. GA was quantified using high-performance liquid chromatography analysis. Total phenolic content (TPC) was assessed using the Folin-Ciocalteu method. The antioxidant activities were evaluated using xanthine oxidase superoxide (XOD-Superoxide) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) assays, while anti-inflammatory activities were examined through lipoxygenase (LOX) and xanthine oxidase (XOD) inhibition assays. Results showed that the water-extracted sample had the highest GA and TPC among the solvents tested, along with the strongest inhibition activities in the XOD-Superoxide and DPPH assays. Both water and ethanol extracts showed significant inhibitory activities in the LOX assay but were inactive in the XOD assay. These findings suggest that the bioactivity of L. pumila leaf extract is associated with GA and TPC. GA and TPC strongly correlated with antioxidant and anti-inflammatory activities, except for the XOD assay. The dataset highlights the potential dietary benefits of L. pumila leaves as a natural source of antioxidants and anti-inflammatory properties for pharmaceutical and nutraceutical applications.

Keywords: Anti-inflammatory; Antioxidant; Gallic acid; Labisia pumila.