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Showing results for sirna tian
Search for Siran Tian instead (3 results)
A Translation-Activating Function of MIWI/piRNA during Mouse Spermiogenesis.
Dai P, Wang X, Gou LT, Li ZT, Wen Z, Chen ZG, Hua MM, Zhong A, Wang L, Su H, Wan H, Qian K, Liao L, Li J, Tian B, Li D, Fu XD, Shi HJ, Zhou Y, Liu MF. Dai P, et al. Cell. 2019 Dec 12;179(7):1566-1581.e16. doi: 10.1016/j.cell.2019.11.022. Cell. 2019. PMID: 31835033 Free PMC article.
Global profiling of RNA-binding protein target sites by LACE-seq.
Su R, Fan LH, Cao C, Wang L, Du Z, Cai Z, Ouyang YC, Wang Y, Zhou Q, Wu L, Zhang N, Zhu X, Lei WL, Zhao H, Tian Y, He S, Wong CCL, Sun QY, Xue Y. Su R, et al. Nat Cell Biol. 2021 Jun;23(6):664-675. doi: 10.1038/s41556-021-00696-9. Epub 2021 Jun 9. Nat Cell Biol. 2021. PMID: 34108658
RNA-binding proteins (RBPs) have essential functions during germline and early embryo development. ...Unexpectedly, transcriptomics and proteomics analysis of Ago2(-/-) oocytes revealed that Ago2 interacts with endogenous small interfering RNAs (endo-siRNA …
RNA-binding proteins (RBPs) have essential functions during germline and early embryo development. ...Unexpectedly, transcriptomics a …
Phase separation of SGS3 drives siRNA body formation and promotes endogenous gene silencing.
Tan H, Luo W, Yan W, Liu J, Aizezi Y, Cui R, Tian R, Ma J, Guo H. Tan H, et al. Cell Rep. 2023 Jan 31;42(1):111985. doi: 10.1016/j.celrep.2022.111985. Epub 2023 Jan 9. Cell Rep. 2023. PMID: 36640363 Free article.
The generation of small interfering RNA (siRNA) involves many RNA processing components, including SUPPRESSOR OF GENE SILENCING 3 (SGS3), RNA-DEPENDENT RNA POLYMERASE 6 (RDR6), and DICER-LIKE proteins (DCLs). ...Dysfunction in tran …
The generation of small interfering RNA (siRNA) involves many RNA processing components, including SUPPRE …
Activation of RARα Receptor Attenuates Neuroinflammation After SAH via Promoting M1-to-M2 Phenotypic Polarization of Microglia and Regulating Mafb/Msr1/PI3K-Akt/NF-κB Pathway.
Tian Y, Liu B, Li Y, Zhang Y, Shao J, Wu P, Xu C, Chen G, Shi H. Tian Y, et al. Front Immunol. 2022 Feb 14;13:839796. doi: 10.3389/fimmu.2022.839796. eCollection 2022. Front Immunol. 2022. PMID: 35237277 Free PMC article.
The RARalpha specific agonist Am80 was injected intraperitoneally 1 hour after SAH. AGN196996 (specific RARalpha inhibitor), Msr1 siRNA and LY294002 (PI3K-Akt inhibitor) were administered via the lateral ventricle before SAH. ...Am80 increased the expression of Mafb and Ms …
The RARalpha specific agonist Am80 was injected intraperitoneally 1 hour after SAH. AGN196996 (specific RARalpha inhibitor), Msr1 siRNA …
siRNA-mediated DNA methylation and H3K9 dimethylation in plants.
Xu C, Tian J, Mo B. Xu C, et al. Protein Cell. 2013 Sep;4(9):656-63. doi: 10.1007/s13238-013-3052-7. Epub 2013 Aug 13. Protein Cell. 2013. PMID: 23943321 Free PMC article. Review.
Heterochromatic siRNAs regulate transcriptional gene silencing by inducing DNA methylation and histone H3K9 dimethylation. ...In this review, we summarize the mechanism of siRNA-mediated epigenetic modification, which involves the production of siRNA and the …
Heterochromatic siRNAs regulate transcriptional gene silencing by inducing DNA methylation and histone H3K9 dimethylation. ...In this …
OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to regulate antiviral immunity.
Xie W, Tian S, Yang J, Cai S, Jin S, Zhou T, Wu Y, Chen Z, Ji Y, Cui J. Xie W, et al. Autophagy. 2022 Oct;18(10):2288-2302. doi: 10.1080/15548627.2022.2026098. Epub 2022 Jan 31. Autophagy. 2022. PMID: 35100065 Free PMC article.
Taken together, our study reveals a specific role of OTUD7B in mediating the activation of cargo receptors in a substrate-dependent manner, which could be a potential target against excessive immune responses.Abbreviations: Baf A(1): bafilomycin A(1); CGAS: cyclic GMP-AMP synthas …
Taken together, our study reveals a specific role of OTUD7B in mediating the activation of cargo receptors in a substrate-dependent manner, …
Effect of surface properties on liposomal siRNA delivery.
Xia Y, Tian J, Chen X. Xia Y, et al. Biomaterials. 2016 Feb;79:56-68. doi: 10.1016/j.biomaterials.2015.11.056. Epub 2015 Dec 2. Biomaterials. 2016. PMID: 26695117 Free PMC article. Review.
Cationic formulations dominate siRNA delivery and neutral formulations also have good performance while anionic formulations are generally not proper for siRNA delivery. ...Effects of ligand modification on cationic and neutral formulations were analyzed. Finally, w …
Cationic formulations dominate siRNA delivery and neutral formulations also have good performance while anionic formulations are gene …
Recent advances in mechanism-based chemotherapy drug-siRNA pairs in co-delivery systems for cancer: A review.
Wang M, Wang J, Li B, Meng L, Tian Z. Wang M, et al. Colloids Surf B Biointerfaces. 2017 Sep 1;157:297-308. doi: 10.1016/j.colsurfb.2017.06.002. Epub 2017 Jun 12. Colloids Surf B Biointerfaces. 2017. PMID: 28601758 Review.
However, little attention has been paid to the extremely complex mechanisms of chemotherapy drug-siRNA pairs during co-delivery process. Proper selection of chemotherapy drug-siRNA pairs is beneficial for achieving desirable cancer therapeutic effects. ...To achieve …
However, little attention has been paid to the extremely complex mechanisms of chemotherapy drug-siRNA pairs during co-delivery proce …
PIWI-interacting RNAs: Critical roles and therapeutic targets in cancer.
Zhou J, Xie H, Liu J, Huang R, Xiang Y, Tian D, Bian E. Zhou J, et al. Cancer Lett. 2023 May 28;562:216189. doi: 10.1016/j.canlet.2023.216189. Epub 2023 Apr 17. Cancer Lett. 2023. PMID: 37076042 Review.
P-element-induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are a novel class of small regulatory RNAs (approximately 24-31 nucleotides in length) that often bind to members of the PIWI protein family. piRNAs regulate transposons in animal germ cells; piRNAs are also s …
P-element-induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are a novel class of small regulatory RNAs (approximately 24-31 nucle …
1,724 results