Overdose of Quetiapine-A Case Report with QT Prolongation

Toxics. 2021 Dec 7;9(12):339. doi: 10.3390/toxics9120339.

Abstract

Quetiapine is an atypical antipsychotic drug used to treat bipolar disorder, schizophrenia, and major depressive disorder. Although several studies describe the adverse effects of intoxication with Quetiapine, only a few report an extreme overdose without comedications that lead to a life threat. We present a case of a 75-year-old male who tried to attempt suicide by ingesting 28 g of Quetiapine. During the management in the emergency department, both serum and urine samples were collected, allowing a complete pharmacokinetic analysis to be conducted, from the admission to the discharge.

Keywords: QT-prolongation; intoxication; quetiapine.

Publication types

  • Case Reports