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Page 1
Inhalation of ZnO Nanoparticles: Splice Junction Expression and Alternative Splicing in Mice.
Rossner P, Vrbova K, Strapacova S, Rossnerova A, Ambroz A, Brzicova T, Libalova H, Javorkova E, Kulich P, Vecera Z, Mikuska P, Coufalik P, Krumal K, Capka L, Docekal B, Moravec P, Sery O, Misek I, Fictum P, Fiser K, Machala M, Topinka J. Rossner P, et al. Among authors: strapacova s. Toxicol Sci. 2019 Mar 1;168(1):190-200. doi: 10.1093/toxsci/kfy288. Toxicol Sci. 2019. PMID: 30500950 Free PMC article.
Environmental six-ring polycyclic aromatic hydrocarbons are potent inducers of the AhR-dependent signaling in human cells.
Vondráček J, Pěnčíková K, Ciganek M, Pivnička J, Karasová M, Hýžďalová M, Strapáčová S, Pálková L, Neča J, Matthews J, Lom MV, Topinka J, Milcová A, Machala M. Vondráček J, et al. Among authors: strapacova s. Environ Pollut. 2020 Nov;266(Pt 2):115125. doi: 10.1016/j.envpol.2020.115125. Epub 2020 Jul 3. Environ Pollut. 2020. PMID: 32679438
Transcriptional and phenotypical alterations associated with a gradual benzo[a]pyrene-induced transition of human bronchial epithelial cells into mesenchymal-like cells.
Hýžďalová M, Procházková J, Straková N, Pěnčíková K, Strapáčová S, Slováčková J, Kajabová S, Líbalová H, Topinka J, Kabátková M, Vondráček J, Mollerup S, Machala M. Hýžďalová M, et al. Among authors: strapacova s. Environ Toxicol Pharmacol. 2024 Apr;107:104424. doi: 10.1016/j.etap.2024.104424. Epub 2024 Mar 22. Environ Toxicol Pharmacol. 2024. PMID: 38522766
A prolonged exposure of human lung carcinoma epithelial cells to benzo[a]pyrene induces p21-dependent epithelial-to-mesenchymal transition (EMT)-like phenotype.
Hýžďalová M, Procházková J, Strapáčová S, Svržková L, Vacek O, Fedr R, Andrysík Z, Hrubá E, Líbalová H, Kléma J, Topinka J, Mašek J, Souček K, Vondráček J, Machala M. Hýžďalová M, et al. Among authors: strapacova s. Chemosphere. 2021 Jan;263:128126. doi: 10.1016/j.chemosphere.2020.128126. Epub 2020 Sep 10. Chemosphere. 2021. PMID: 33297115
Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands.
Procházková J, Strapáčová S, Svržková L, Andrysík Z, Hýžďalová M, Hrubá E, Pěnčíková K, Líbalová H, Topinka J, Kléma J, Espinosa JM, Vondráček J, Machala M. Procházková J, et al. Among authors: strapacova s. Toxicol Lett. 2018 Aug;292:162-174. doi: 10.1016/j.toxlet.2018.04.024. Epub 2018 Apr 25. Toxicol Lett. 2018. PMID: 29704546
In vitro profiling of toxic effects of prominent environmental lower-chlorinated PCB congeners linked with endocrine disruption and tumor promotion.
Pěnčíková K, Svržková L, Strapáčová S, Neča J, Bartoňková I, Dvořák Z, Hýžďalová M, Pivnička J, Pálková L, Lehmler HJ, Li X, Vondráček J, Machala M. Pěnčíková K, et al. Among authors: strapacova s. Environ Pollut. 2018 Jun;237:473-486. doi: 10.1016/j.envpol.2018.02.067. Epub 2018 Mar 15. Environ Pollut. 2018. PMID: 29518658 Free PMC article.
Consensus toxicity factors for polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls combining in silico models and extensive in vitro screening of AhR-mediated effects in human and rodent cells.
Larsson M, van den Berg M, Brenerová P, van Duursen MB, van Ede KI, Lohr C, Luecke-Johansson S, Machala M, Neser S, Pěnčíková K, Poellinger L, Schrenk D, Strapáčová S, Vondráček J, Andersson PL. Larsson M, et al. Among authors: strapacova s. Chem Res Toxicol. 2015 Apr 20;28(4):641-50. doi: 10.1021/tx500434j. Epub 2015 Feb 13. Chem Res Toxicol. 2015. PMID: 25654323