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PAX5 fusion genes are frequent in poor risk childhood acute lymphoblastic leukaemia and can be targeted with BIBF1120.
Fazio G, Bresolin S, Silvestri D, Quadri M, Saitta C, Vendramini E, Buldini B, Palmi C, Bardini M, Grioni A, Rigamonti S, Galbiati M, Mecca S, Savino AM, Peloso A, Tu JW, Bhatia S, Borkhardt A, Micalizzi C, Lo Nigro L, Locatelli F, Conter V, Rizzari C, Valsecchi MG, Te Kronnie G, Biondi A, Cazzaniga G. Fazio G, et al. Among authors: rigamonti s. EBioMedicine. 2022 Sep;83:104224. doi: 10.1016/j.ebiom.2022.104224. Epub 2022 Aug 16. EBioMedicine. 2022. PMID: 35985167 Free PMC article.
Case report: Cytopenias in VEXAS syndrome - a WHO 2022 based approach in a single-center cohort.
Diral E, Campochiaro C, Tomelleri A, Bergonzi GM, Pizzano U, Ponzoni M, Bongiovanni L, Ronchi P, Tresoldi C, Rigamonti S, Scarfò F, Latino GM, Rinaldi E, Bernardi M, Dagna L, Ciceri F. Diral E, et al. Among authors: rigamonti s. Front Immunol. 2024 Jan 25;15:1354130. doi: 10.3389/fimmu.2024.1354130. eCollection 2024. Front Immunol. 2024. PMID: 38333211 Free PMC article.
A Simple RNA Target Capture NGS Strategy for Fusion Genes Assessment in the Diagnostics of Pediatric B-cell Acute Lymphoblastic Leukemia.
Grioni A, Fazio G, Rigamonti S, Bystry V, Daniele G, Dostalova Z, Quadri M, Saitta C, Silvestri D, Songia S, Storlazzi CT, Biondi A, Darzentas N, Cazzaniga G. Grioni A, et al. Among authors: rigamonti s. Hemasphere. 2019 Jun 4;3(3):e250. doi: 10.1097/HS9.0000000000000250. eCollection 2019 Jun. Hemasphere. 2019. PMID: 31723839 Free PMC article.