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(Pyrrolo-pyridin-5-yl)benzamides: BBB permeable monoamine oxidase B inhibitors with neuroprotective effect on cortical neurons.
Eur J Med Chem. 2019 Jan 15;162:793-809. doi: 10.1016/j.ejmech.2018.11.009. Epub 2018 Nov 13.
Eur J Med Chem. 2019.
PMID: 30522087
Carboxamides vs. methanimines: Crystal structures, binding interactions, photophysical studies, and biological evaluation of (indazole-5-yl)methanimines as monoamine oxidase B and acetylcholinesterase inhibitors.
Tzvetkov NT, Stammler HG, Georgieva MG, Russo D, Faraone I, Balacheva AA, Hristova S, Atanasov AG, Milella L, Antonov L, Gastreich M.
Tzvetkov NT, et al. Among authors: hristova s.
Eur J Med Chem. 2019 Oct 1;179:404-422. doi: 10.1016/j.ejmech.2019.06.041. Epub 2019 Jun 19.
Eur J Med Chem. 2019.
PMID: 31265934
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Crystal structures, binding interactions, and ADME evaluation of brain penetrant N-substituted indazole-5-carboxamides as subnanomolar, selective monoamine oxidase B and dual MAO-A/B inhibitors.
Tzvetkov NT, Stammler HG, Neumann B, Hristova S, Antonov L, Gastreich M.
Tzvetkov NT, et al. Among authors: hristova s.
Eur J Med Chem. 2017 Feb 15;127:470-492. doi: 10.1016/j.ejmech.2017.01.011. Epub 2017 Jan 11.
Eur J Med Chem. 2017.
PMID: 28107736
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