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Page 1
The melanocortin pathway and energy homeostasis: From discovery to obesity therapy.
Mol Metab. 2021 Jun;48:101206. doi: 10.1016/j.molmet.2021.101206. Epub 2021 Mar 6.
Mol Metab. 2021.
PMID: 33684608
Free PMC article.
Review.
Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency.
Collet TH, Dubern B, Mokrosinski J, Connors H, Keogh JM, Mendes de Oliveira E, Henning E, Poitou-Bernert C, Oppert JM, Tounian P, Marchelli F, Alili R, Le Beyec J, Pépin D, Lacorte JM, Gottesdiener A, Bounds R, Sharma S, Folster C, Henderson B, O'Rahilly S, Stoner E, Gottesdiener K, Panaro BL, Cone RD, Clément K, Farooqi IS, Van der Ploeg LHT.
Collet TH, et al. Among authors: sharma s.
Mol Metab. 2017 Oct;6(10):1321-1329. doi: 10.1016/j.molmet.2017.06.015. Epub 2017 Jul 8.
Mol Metab. 2017.
PMID: 29031731
Free PMC article.
Clinical Trial.
Item in Clipboard
Current Mechanistic and Pharmacodynamic Understanding of Melanocortin-4 Receptor Activation.
Sharma S, Garfield AS, Shah B, Kleyn P, Ichetovkin I, Moeller IH, Mowrey WR, Van der Ploeg LHT.
Sharma S, et al.
Molecules. 2019 May 16;24(10):1892. doi: 10.3390/molecules24101892.
Molecules. 2019.
PMID: 31100979
Free PMC article.
Review.
Item in Clipboard
Melanocortins in the treatment of male and female sexual dysfunction.
Shadiack AM, Sharma SD, Earle DC, Spana C, Hallam TJ.
Shadiack AM, et al. Among authors: sharma sd.
Curr Top Med Chem. 2007;7(11):1137-44. doi: 10.2174/156802607780906681.
Curr Top Med Chem. 2007.
PMID: 17584134
Review.
Item in Clipboard
MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency.
Clément K, Biebermann H, Farooqi IS, Van der Ploeg L, Wolters B, Poitou C, Puder L, Fiedorek F, Gottesdiener K, Kleinau G, Heyder N, Scheerer P, Blume-Peytavi U, Jahnke I, Sharma S, Mokrosinski J, Wiegand S, Müller A, Weiß K, Mai K, Spranger J, Grüters A, Blankenstein O, Krude H, Kühnen P.
Clément K, et al. Among authors: sharma s.
Nat Med. 2018 May;24(5):551-555. doi: 10.1038/s41591-018-0015-9. Epub 2018 May 7.
Nat Med. 2018.
PMID: 29736023
Clinical Trial.
Item in Clipboard
Preclinical gastrointestinal prokinetic efficacy and endocrine effects of the ghrelin mimetic RM-131.
Van der Ploeg L, Laken H, Sharma S, Datta R, Halem H, Dong J, Touvay C, Teillot M, Noonan P, Tartaglia L, Stoner L, Henderson B, Gottesdiener K, Culler M.
Van der Ploeg L, et al. Among authors: sharma s.
Life Sci. 2014 Jul 25;109(1):20-9. doi: 10.1016/j.lfs.2014.06.003. Epub 2014 Jun 12.
Life Sci. 2014.
PMID: 24931905
Item in Clipboard
Imaging thromboembolism with fibrin-avid 99mTc-peptide: evaluation in swine.
Aruva MR, Daviau J, Sharma SS, Thakur ML.
Aruva MR, et al. Among authors: sharma ss.
J Nucl Med. 2006 Jan;47(1):155-62.
J Nucl Med. 2006.
PMID: 16391200
Free PMC article.
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