A new 2-(2'-hydroxyphenyl)quinazolin-4(3H)-one derived acylhydrazone for fluorescence recognition of Al3

Lijun Tang; Shuangli Ding; Keli Zhong; Shuhua Hou; Yanjiang Bian; Xiaomei Yan

doi:10.1016/j.saa.2016.11.026

A new 2-(2'-hydroxyphenyl)quinazolin-4(3H)-one derived acylhydrazone for fluorescence recognition of Al³

Spectrochim Acta A Mol Biomol Spectrosc. 2017 Mar 5:174:70-74. doi: 10.1016/j.saa.2016.11.026. Epub 2016 Nov 20.

Authors

Lijun Tang¹, Shuangli Ding², Keli Zhong², Shuhua Hou², Yanjiang Bian², Xiaomei Yan³

Affiliations

¹ Department of Chemistry, Bohai University, Jinzhou 121013, China. Electronic address: ljtang@bhu.edu.cn.
² Department of Chemistry, Bohai University, Jinzhou 121013, China.
³ College of Laboratory Medicine, Dalian Medical University, Dalian 116044, China. Electronic address: xmyan1978@sina.com.

PMID: 27886645
DOI: 10.1016/j.saa.2016.11.026

Abstract

A new 2-(2'-hydroxyphenyl)quinazolin-4(3H)-one derived acylhydrazone (QP) was designed and synthesized as a fluorescent sensor. In Tris∙HCl buffer (10mM, pH7.4)/ethanol (1/9, v/v) solution, QP exhibits a highly selective fluorescence response to Al³⁺ over other metal ions with a significant blue-shifted and enhanced emission at 473nm. QP interacts with Al³⁺ reversibly through a 1:2 binding ratio with a detection limit of 4.79×10^-8M. Potential applicability of QP for Al³⁺ detection in tap and lake water samples were also examined by 'proof-of-concept' experiments.

Keywords: Acylhydrazone; Aluminum(III) recognition; CHEF; ESIPT; Quinazolin-4(3H)-one.