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Bioactive components and the molecular mechanism of Shengxian Decoction against lung adenocarcinoma based on network pharmacology and molecular docking.
Yuan R, Li K, Li Q, Wang C, Zhang H, Ge L, Ren Y, You F. Yuan R, et al. Am J Transl Res. 2023 Dec 15;15(12):6988-7012. eCollection 2023. Am J Transl Res. 2023. PMID: 38186989 Free PMC article.
OBJECTIVE: The aim of this study was to identify the active components of Shengxian Decoction (SXT) and to elucidate the multi-component, multi-target, and multi-pathway regulatory mechanisms underlying the efficacy of SXT in treating lung adenocarcinoma (LUAD). ...
OBJECTIVE: The aim of this study was to identify the active components of Shengxian Decoction (SXT) and to elucidate the multi-compon …
[Effective components of Shengxian Decoction and its mechanism of action in treating chronic heart failure based on UHPLC-Q-TOF-MS integrated with network pharmacology].
Ma Y, Wang BL, Wang L, Huang CY, Sun M, Jiao GY, Zhang F, Chen WS. Ma Y, et al. Zhongguo Zhong Yao Za Zhi. 2021 May;46(10):2489-2500. doi: 10.19540/j.cnki.cjcmm.20200915.201. Zhongguo Zhong Yao Za Zhi. 2021. PMID: 34047095 Chinese.
This study aimed to elucidate the effective components of Shengxian Decoction and its mechanism of action in treating chronic heart failure. ...This study provided a scientific basis for mechanism and effective ingredients of Shengxian Decoction....
This study aimed to elucidate the effective components of Shengxian Decoction and its mechanism of action in treating chronic heart f …
Genetic diversity and selection signatures of four indigenous pig breeds from eastern China.
Chen Z, Ye X, Zhang Z, Zhao Q, Xiang Y, Xu N, Wang Q, Pan Y, Guo X, Wang Z. Chen Z, et al. Anim Genet. 2022 Aug;53(4):506-509. doi: 10.1111/age.13208. Epub 2022 Apr 30. Anim Genet. 2022. PMID: 35489815
To investigate the population structure and genetic diversity of Jinhua (JH), Longyou Black (LYW), Shengxian Spotted (SXH), and Lanxi Spotted (LXH) breeds, a total of 200 pigs belonging to 10 diverse population were genotyped using SNP chips. ...
To investigate the population structure and genetic diversity of Jinhua (JH), Longyou Black (LYW), Shengxian Spotted (SXH), and Lanxi …
Genome-wide epistatic interactions of litter size at birth in Chinese indigenous pigs.
Chen Z, Li Y, Zhang Z, Zhao W, Zhang Z, Xiang Y, Wang Q, Pan Y, Guo X, Wang Z. Chen Z, et al. Anim Genet. 2021 Oct;52(5):739-743. doi: 10.1111/age.13120. Epub 2021 Jul 21. Anim Genet. 2021. PMID: 34291500
Herein, we conducted genome scans of epistatic interactions underlying TNB and NBA traits in a total of 150 Chinese indigenous pigs (75 Jinhua and 75 Shengxian Spotted pigs) with high throughput genomic data. Based on SNPs with high interaction values and connectivity scor …
Herein, we conducted genome scans of epistatic interactions underlying TNB and NBA traits in a total of 150 Chinese indigenous pigs (75 Jinh …
Genetic diversity analyses of 10 indigenous Chinese pig populations based on 20 microsatellites.
Li SJ, Yang SL, Zhao SH, Fan B, Yu M, Wang HS, Li MH, Liu B, Xiong TA, Li K. Li SJ, et al. J Anim Sci. 2004 Feb;82(2):368-74. doi: 10.2527/2004.822368x. J Anim Sci. 2004. PMID: 14974533
The observed heterozygosities were in the range of 0.31 (Duroc) to 0.66 (Shengxian). The F(IS) value was in a range of -0.07 to 0.48. The mean F(ST) showed that approximately 78% of the genetic variation was within-population and 22% was across the populations. ...The othe …
The observed heterozygosities were in the range of 0.31 (Duroc) to 0.66 (Shengxian). The F(IS) value was in a range of -0.07 to 0.48. …
Identifying the unique characteristics of the Chinese indigenous pig breeds in the Yangtze River Delta region for precise conservation.
Zhao QB, Oyelami FO, Qadri QR, Sun H, Xu Z, Wang QS, Pan YC. Zhao QB, et al. BMC Genomics. 2021 Mar 2;22(1):151. doi: 10.1186/s12864-021-07476-7. BMC Genomics. 2021. PMID: 33653278 Free PMC article.

A total of 37,514 significant specific SNPs (p < 0.01) were obtained from these breeds, and the Chinese local pig breed with the most significant SNPs was Hongdenglong (HD), followed by Jiaxing black (JX), Huaibei (HB), Bihu (BH), small Meishan (SMS), Shengxian Hua (SH)

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A total of 37,514 significant specific SNPs (p < 0.01) were obtained from these breeds, and the Chinese local pig breed with the most sig

…
[Studies of the relationship of melanocortin receptor 1(MC1R) gene with coat color phenotype in pigs].
Deng SH, Gao J, Ren J, Chen KF, Ding NS, Ai HS, Lin WH, Wang WJ, Liu BS, Lai FJ, Huang LS. Deng SH, et al. Yi Chuan Xue Bao. 2003 Oct;30(10):949-54. Yi Chuan Xue Bao. 2003. PMID: 14669512 Chinese.
PCR-Acc II-RFLP, PCR-BspH I-RFLP and PCR-SSCP were used in combination to analyze genotype at MC1R locus among individuals from 16 full-sib pedigrees and 6 Chinese native breeds including Jinhua, Jiaxing Black, Yushan Black, Leping Spotted, Shanggao Spotted and Shengxian S …
PCR-Acc II-RFLP, PCR-BspH I-RFLP and PCR-SSCP were used in combination to analyze genotype at MC1R locus among individuals from 16 full-sib …