Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 1
1986 2
1987 1
1988 2
1989 3
1990 4
1991 5
1992 6
1993 3
1994 2
1995 4
1996 6
1997 7
1998 13
1999 10
2000 6
2001 20
2002 17
2003 31
2004 26
2005 33
2006 56
2007 57
2008 77
2009 74
2010 126
2011 175
2012 217
2013 219
2014 222
2015 288
2016 278
2017 311
2018 368
2019 428
2020 505
2021 593
2022 680
2023 787
2024 254

Text availability

Article attribute

Article type

Publication date

Search Results

5,325 results

Results by year

Filters applied: . Clear all
Page 1
Showing results for shaping gao
Search for Shaoping Gao instead (3 results)
SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology.
Huang J, Wu C, Kloeber JA, Gao H, Gao M, Zhu Q, Chang Y, Zhao F, Guo G, Luo K, Dai H, Liu S, Huang Q, Kim W, Zhou Q, Zhu S, Wu Z, Tu X, Yin P, Deng M, Wang L, Yuan J, Lou Z. Huang J, et al. Mol Cell. 2023 Apr 6;83(7):1043-1060.e10. doi: 10.1016/j.molcel.2023.02.004. Epub 2023 Feb 27. Mol Cell. 2023. PMID: 36854302
Using super-resolution imaging, we find that SLFN5 binds to 53BP1 chromatin domains to assemble a higher-order microdomain architecture by driving damaged chromatin dynamics at both DSBs and deprotected telomeres. Mechanistically, we propose that 53BP1 topology is shaped b …
Using super-resolution imaging, we find that SLFN5 binds to 53BP1 chromatin domains to assemble a higher-order microdomain architecture by d …
mTOR-mediated metabolic reprogramming shapes distinct microglia functions in response to lipopolysaccharide and ATP.
Hu Y, Mai W, Chen L, Cao K, Zhang B, Zhang Z, Liu Y, Lou H, Duan S, Gao Z. Hu Y, et al. Glia. 2020 May;68(5):1031-1045. doi: 10.1002/glia.23760. Epub 2019 Dec 3. Glia. 2020. PMID: 31793691
Our study reveals a critical role for mTOR in the regulation of metabolic programming of microglia to shape their distinct functions under different states and shed light on the potential application of targeting metabolism to interfere with microglia-mediated neuroinflamm …
Our study reveals a critical role for mTOR in the regulation of metabolic programming of microglia to shape their distinct functions …
Shaping Tumor Microenvironment for Improving Nanoparticle Delivery.
Gao H. Gao H. Curr Drug Metab. 2016;17(8):731-736. doi: 10.2174/1389200217666160630203600. Curr Drug Metab. 2016. PMID: 27396754 Review.
RESULTS: In tumor, elevated interstitial fluid pressure, abnormal tumor vasculature, dense tumor extracellular matrix and elevated solid stress considerably hinder the extravasation and intratumor penetration of nanoparticles. Therefore, shaping the tumor microenvironment …
RESULTS: In tumor, elevated interstitial fluid pressure, abnormal tumor vasculature, dense tumor extracellular matrix and elevated solid str …
Recent Advances in 4D Bioprinting.
Yang Q, Gao B, Xu F. Yang Q, et al. Biotechnol J. 2020 Jan;15(1):e1900086. doi: 10.1002/biot.201900086. Epub 2019 Sep 20. Biotechnol J. 2020. PMID: 31486199 Review.
In this technique, the printed bioconstructs are able to change their shapes or functionalities when triggered by either internal or external stimuli. In 4D bioprinting, the materials with/without cells enable the spatial-temporal control of the shape and/or functio …
In this technique, the printed bioconstructs are able to change their shapes or functionalities when triggered by either internal or …
Reinforcement Learning Control With Knowledge Shaping.
Gao X, Si J, Huang H. Gao X, et al. IEEE Trans Neural Netw Learn Syst. 2024 Mar;35(3):3156-3167. doi: 10.1109/TNNLS.2023.3243631. Epub 2024 Feb 29. IEEE Trans Neural Netw Learn Syst. 2024. PMID: 37027592
Toward this goal, we formalize knowledge transfer by expressing knowledge in the value function in our problem construct, which is referred to as reinforcement learning with knowledge shaping (RL-KS). Unlike most transfer learning studies that are empirical in nature, our …
Toward this goal, we formalize knowledge transfer by expressing knowledge in the value function in our problem construct, which is referred …
Sexual behavior shapes male genitourinary microbiome composition.
Toh E, Xing Y, Gao X, Jordan SJ, Batteiger TA, Batteiger BE, Van Der Pol B, Muzny CA, Gebregziabher N, Williams JA, Fortenberry LJ, Fortenberry JD, Dong Q, Nelson DE. Toh E, et al. Cell Rep Med. 2023 Mar 21;4(3):100981. doi: 10.1016/j.xcrm.2023.100981. Cell Rep Med. 2023. PMID: 36948151 Free PMC article.
Thus, the male urethra supports a simple core microbiome that is established independent of sexual exposures but can be re-shaped by vaginal sex. Overall, the results suggest that urogenital microbiology and sexual behavior are inexorably intertwined, and show that the mal …
Thus, the male urethra supports a simple core microbiome that is established independent of sexual exposures but can be re-shaped by …
Structures and recognition modes of toll-like receptors.
Gao D, Li W. Gao D, et al. Proteins. 2017 Jan;85(1):3-9. doi: 10.1002/prot.25179. Epub 2016 Oct 24. Proteins. 2017. PMID: 27699870 Review.
Despite the differences in interaction areas of ligand with TLRs, the extracellular domains of TLRs all adopt horseshoe-shaped structures and the overall M-shape of the TLR-ligand complexes is strikingly similar. ...
Despite the differences in interaction areas of ligand with TLRs, the extracellular domains of TLRs all adopt horseshoe-shaped struct …
Apex structures enhance water drainage on leaves.
Wang T, Si Y, Dai H, Li C, Gao C, Dong Z, Jiang L. Wang T, et al. Proc Natl Acad Sci U S A. 2020 Jan 28;117(4):1890-1894. doi: 10.1073/pnas.1909924117. Epub 2020 Jan 14. Proc Natl Acad Sci U S A. 2020. PMID: 31937663 Free PMC article.
We demonstrate that the apex structure enhances water drainage on the leaf by employing a curvature-controlled mechanism that is based on shaping a balance between reduced capillarity and enhanced gravity components. The leaf apex shape changes from round to triangl …
We demonstrate that the apex structure enhances water drainage on the leaf by employing a curvature-controlled mechanism that is based on …
From sensing to shaping microbiota: insights into the role of NOD2 in intestinal homeostasis and progression of Crohn's disease.
Balasubramanian I, Gao N. Balasubramanian I, et al. Am J Physiol Gastrointest Liver Physiol. 2017 Jul 1;313(1):G7-G13. doi: 10.1152/ajpgi.00330.2016. Epub 2017 Apr 27. Am J Physiol Gastrointest Liver Physiol. 2017. PMID: 28450278 Free PMC article. Review.
In addition to sensing its specific bacterial components as a cytosolic pattern recognition receptor, NOD2 also appears to shape the colonization of intestinal microbiota. Activated NOD2 triggers downstream signaling cascades exampled by the NF-kappaB pathway to induce ant …
In addition to sensing its specific bacterial components as a cytosolic pattern recognition receptor, NOD2 also appears to shape the …
Depth-based shape-analysis.
Hong Y, Gao Y, Niethammer M, Bouix S. Hong Y, et al. Med Image Comput Comput Assist Interv. 2014;17(Pt 3):17-24. doi: 10.1007/978-3-319-10443-0_3. Med Image Comput Comput Assist Interv. 2014. PMID: 25320777
In this paper we propose a new method for shape analysis based on the depth-ordering of shapes. We use this depth-ordering to non-parametrically define depth with respect to a normal control population. ...We combine this approach with a permutation test allowing it …
In this paper we propose a new method for shape analysis based on the depth-ordering of shapes. We use this depth-ordering to …
5,325 results