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Year Number of Results
2007 1
2008 2
2009 1
2010 2
2011 1
2012 5
2013 4
2018 1
2020 1
2023 1
2024 1

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17 results

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Page 1
Pacritinib is a potent ACVR1 inhibitor with significant anemia benefit in patients with myelofibrosis.
Oh ST, Mesa RA, Harrison CN, Bose P, Gerds AT, Gupta V, Scott BL, Kiladjian JJ, Lucchesi A, Kong T, Buckley SA, Tyavanagimatt S, Harder BG, Roman-Torres K, Smith J, Craig AR, Mascarenhas J, Verstovsek S. Oh ST, et al. Among authors: tyavanagimatt s. Blood Adv. 2023 Oct 10;7(19):5835-5842. doi: 10.1182/bloodadvances.2023010151. Blood Adv. 2023. PMID: 37552106 Free PMC article.
Identification and Characterization of a Small Molecule Bcl-2 Functional Converter.
Kopparapu PR, Pearce MC, Löhr CV, Duong C, Jang HS, Tyavanagimatt S, O'Donnell EF 3rd, Nakshatri H, Kolluri SK. Kopparapu PR, et al. Among authors: tyavanagimatt s. Cancer Res Commun. 2024 Mar 4;4(3):634-644. doi: 10.1158/2767-9764.CRC-22-0526. Cancer Res Commun. 2024. PMID: 38329389 Free PMC article.
A potent Lassa virus antiviral targets an arenavirus virulence determinant.
Madu IG, Files M, Gharaibeh DN, Moore AL, Jung KH, Gowen BB, Dai D, Jones KF, Tyavanagimatt SR, Burgeson JR, Korth MJ, Bedard KM, Iadonato SP, Amberg SM. Madu IG, et al. Among authors: tyavanagimatt sr. PLoS Pathog. 2018 Dec 21;14(12):e1007439. doi: 10.1371/journal.ppat.1007439. eCollection 2018 Dec. PLoS Pathog. 2018. PMID: 30576397 Free PMC article.
Determining the recommended dose of pacritinib: results from the PAC203 dose-finding trial in advanced myelofibrosis.
Gerds AT, Savona MR, Scott BL, Talpaz M, Egyed M, Harrison CN, Yacoub A, Vannucchi A, Mead AJ, Kiladjian JJ, O'Sullivan J, García-Gutiérrez V, Bose P, Rampal RK, Miller CB, Palmer J, Oh ST, Buckley SA, Mould DR, Ito K, Tyavanagimatt S, Smith JA, Roman-Torres K, Devineni S, Craig AR, Mascarenhas JO. Gerds AT, et al. Among authors: tyavanagimatt s. Blood Adv. 2020 Nov 24;4(22):5825-5835. doi: 10.1182/bloodadvances.2020003314. Blood Adv. 2020. PMID: 33232476 Free PMC article. Clinical Trial.
Development of ST-246® for Treatment of Poxvirus Infections.
Jordan R, Leeds JM, Tyavanagimatt S, Hruby DE. Jordan R, et al. Among authors: tyavanagimatt s. Viruses. 2010 Nov;2(11):2409-2435. doi: 10.3390/v2112409. Epub 2010 Nov 3. Viruses. 2010. PMID: 21994624 Free PMC article.
A novel inhibitor of dengue virus replication that targets the capsid protein.
Byrd CM, Dai D, Grosenbach DW, Berhanu A, Jones KF, Cardwell KB, Schneider C, Wineinger KA, Page JM, Harver C, Stavale E, Tyavanagimatt S, Stone MA, Bartenschlager R, Scaturro P, Hruby DE, Jordan R. Byrd CM, et al. Among authors: tyavanagimatt s. Antimicrob Agents Chemother. 2013 Jan;57(1):15-25. doi: 10.1128/AAC.01429-12. Epub 2012 Oct 15. Antimicrob Agents Chemother. 2013. PMID: 23070172 Free PMC article.
Pharmacokinetic and pharmacodynamic modeling to determine the dose of ST-246 to protect against smallpox in humans.
Leeds JM, Fenneteau F, Gosselin NH, Mouksassi MS, Kassir N, Marier JF, Chen Y, Grosenbach D, Frimm AE, Honeychurch KM, Chinsangaram J, Tyavanagimatt SR, Hruby DE, Jordan R. Leeds JM, et al. Among authors: tyavanagimatt sr. Antimicrob Agents Chemother. 2013 Mar;57(3):1136-43. doi: 10.1128/AAC.00959-12. Epub 2012 Dec 17. Antimicrob Agents Chemother. 2013. PMID: 23254433 Free PMC article.
Novel benzoxazole inhibitor of dengue virus replication that targets the NS3 helicase.
Byrd CM, Grosenbach DW, Berhanu A, Dai D, Jones KF, Cardwell KB, Schneider C, Yang G, Tyavanagimatt S, Harver C, Wineinger KA, Page J, Stavale E, Stone MA, Fuller KP, Lovejoy C, Leeds JM, Hruby DE, Jordan R. Byrd CM, et al. Among authors: tyavanagimatt s. Antimicrob Agents Chemother. 2013 Apr;57(4):1902-12. doi: 10.1128/AAC.02251-12. Epub 2013 Feb 12. Antimicrob Agents Chemother. 2013. PMID: 23403421 Free PMC article.
Safety and pharmacokinetics of the antiorthopoxvirus compound ST-246 following repeat oral dosing in healthy adult subjects.
Jordan R, Chinsangaram J, Bolken TC, Tyavanagimatt SR, Tien D, Jones KF, Frimm A, Corrado ML, Pickens M, Landis P, Clarke J, Marbury TC, Hruby DE. Jordan R, et al. Among authors: tyavanagimatt sr. Antimicrob Agents Chemother. 2010 Jun;54(6):2560-6. doi: 10.1128/AAC.01689-09. Epub 2010 Apr 12. Antimicrob Agents Chemother. 2010. PMID: 20385870 Free PMC article. Clinical Trial.
17 results