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Page 1
RABL6A Regulates Schwann Cell Senescence in an RB1-Dependent Manner.
Kohlmeyer JL, Kaemmer CA, Umesalma S, Gourronc FA, Klingelhutz AJ, Quelle DE. Kohlmeyer JL, et al. Among authors: umesalma s. Int J Mol Sci. 2021 May 20;22(10):5367. doi: 10.3390/ijms22105367. Int J Mol Sci. 2021. PMID: 34065204 Free PMC article.
RABL6A Promotes Pancreatic Neuroendocrine Tumor Angiogenesis and Progression In Vivo.
Maharjan CK, Umesalma S, Kaemmer CA, Muniz VP, Bauchle C, Mott SL, Zamba KD, Breheny P, Leidinger MR, Darbro BW, Stephens SB, Meyerholz DK, Quelle DE. Maharjan CK, et al. Among authors: umesalma s. Biomedicines. 2021 Jun 2;9(6):633. doi: 10.3390/biomedicines9060633. Biomedicines. 2021. PMID: 34199469 Free PMC article.
Gene Expression Signatures Identify Novel Therapeutics for Metastatic Pancreatic Neuroendocrine Tumors.
Scott AT, Weitz M, Breheny PJ, Ear PH, Darbro B, Brown BJ, Braun TA, Li G, Umesalma S, Kaemmer CA, Maharjan CK, Quelle DE, Bellizzi AM, Chandrasekharan C, Dillon JS, O'Dorisio TM, Howe JR. Scott AT, et al. Among authors: umesalma s. Clin Cancer Res. 2020 Apr 15;26(8):2011-2021. doi: 10.1158/1078-0432.CCR-19-2884. Epub 2020 Jan 14. Clin Cancer Res. 2020. PMID: 31937620 Free PMC article.
A porcine model of neurofibromatosis type 1 that mimics the human disease.
White KA, Swier VJ, Cain JT, Kohlmeyer JL, Meyerholz DK, Tanas MR, Uthoff J, Hammond E, Li H, Rohret FA, Goeken A, Chan CH, Leidinger MR, Umesalma S, Wallace MR, Dodd RD, Panzer K, Tang AH, Darbro BW, Moutal A, Cai S, Li W, Bellampalli SS, Khanna R, Rogers CS, Sieren JC, Quelle DE, Weimer JM. White KA, et al. Among authors: umesalma s. JCI Insight. 2018 Jun 21;3(12):e120402. doi: 10.1172/jci.insight.120402. eCollection 2018 Jun 21. JCI Insight. 2018. PMID: 29925695 Free PMC article.
RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth.
Umesalma S, Kaemmer CA, Kohlmeyer JL, Letney B, Schab AM, Reilly JA, Sheehy RM, Hagen J, Tiwari N, Zhan F, Leidinger MR, O'Dorisio TM, Dillon J, Merrill RA, Meyerholz DK, Perl AL, Brown BJ, Braun TA, Scott AT, Ginader T, Taghiyev AF, Zamba GK, Howe JR, Strack S, Bellizzi AM, Narla G, Darbro BW, Quelle FW, Quelle DE. Umesalma S, et al. J Clin Invest. 2019 Mar 4;129(4):1641-1653. doi: 10.1172/JCI123049. eCollection 2019 Mar 4. J Clin Invest. 2019. PMID: 30721156 Free PMC article.
Histone demethylase PHF8 regulates hypoxia signaling through HIF1α and H3K4me3.
Maina PK, Shao P, Jia X, Liu Q, Umesalma S, Marin M, Long D Jr, Concepción-Román S, Qi HH. Maina PK, et al. Among authors: umesalma s. Biochim Biophys Acta Gene Regul Mech. 2017 Sep;1860(9):1002-1012. doi: 10.1016/j.bbagrm.2017.07.005. Epub 2017 Jul 20. Biochim Biophys Acta Gene Regul Mech. 2017. PMID: 28734980 Free PMC article.
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