Transfer learning based novel ensemble classifier for COVID-19 detection from chest CT-scans

Comput Biol Med. 2022 Feb:141:105127. doi: 10.1016/j.compbiomed.2021.105127. Epub 2021 Dec 11.

Abstract

Coronavirus Disease 2019 (COVID-19) is a deadly infection that affects the respiratory organs in humans as well as animals. By 2020, this disease turned out to be a pandemic affecting millions of individuals across the globe. Conducting rapid tests for a large number of suspects preventing the spread of the virus has become a challenge. In the recent past, several deep learning based approaches have been developed for automating the process of detecting COVID-19 infection from Lung Computerized Tomography (CT) scan images. However, most of them rely on a single model prediction for the final decision which may or may not be accurate. In this paper, we propose a novel ensemble approach that aggregates the strength of multiple deep neural network architectures before arriving at the final decision. We use various pre-trained models such as VGG16, VGG19, InceptionV3, ResNet50, ResNet50V2, InceptionResNetV2, Xception, and MobileNet and fine-tune them using Lung CT Scan images. All these trained models are further used to create a strong ensemble classifier that makes the final prediction. Our experiments exhibit that the proposed ensemble approach is superior to existing ensemble approaches and set state-of-the-art results for detecting COVID-19 infection from lung CT scan images.

Keywords: Computerized tomography (CT); Coronavirus disease 2019; Ensemble classifier; Pre-trained models; Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2); Transfer learning.

MeSH terms

  • COVID-19*
  • Deep Learning*
  • Humans
  • Pandemics
  • SARS-CoV-2
  • Tomography, X-Ray Computed