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The effects of β-D-mannuronic acid (M2000), as a novel NSAID, on COX1 and COX2 activities and gene expression in ankylosing spondylitis patients and the murine monocyte/macrophage, J774 cell line.
Jafarnezhad-Ansariha F, Yekaninejad MS, Jamshidi AR, Mansouri R, Vojdanian M, Mahmoudi M, Fattahi MJ, Hashemi SN, Rehm BHA, Matsuo H, Esposito E, Cuzzocrea S, Mirshafiey A. Jafarnezhad-Ansariha F, et al. Among authors: hashemi sn. Inflammopharmacology. 2018 Apr;26(2):375-384. doi: 10.1007/s10787-017-0386-4. Epub 2017 Aug 17. Inflammopharmacology. 2018. PMID: 28819782 Clinical Trial.
Evaluation of the efficacy and safety of β-d-mannuronic acid in patients with ankylosing spondylitis: A 12-week randomized, placebo-controlled, phase I/II clinical trial.
Fattahi MJ, Jamshidi AR, Mahmoudi M, Vojdanian M, Yekaninejad MS, Jafarnezhad-Ansariha F, Ahmadi H, Rehm BHA, Matsuo H, Cuzzocrea S, Hosseini M, Hashemi SN, Aghazadeh Z, Mirshafiey A. Fattahi MJ, et al. Among authors: hashemi sn. Int Immunopharmacol. 2018 Jan;54:112-117. doi: 10.1016/j.intimp.2017.11.003. Epub 2017 Nov 8. Int Immunopharmacol. 2018. PMID: 29127910 Clinical Trial.