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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 2
2004 2
2005 1
2006 8
2007 7
2008 7
2009 9
2010 14
2011 10
2012 12
2013 10
2014 7
2015 13
2016 12
2017 10
2018 9
2019 12
2020 6
2021 17
2022 6
2023 7
2024 3

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168 results

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Page 1
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.
de Vries LE, Jansen PAM, Barcelo C, Munro J, Verhoef JMJ, Pasaje CFA, Rubiano K, Striepen J, Abla N, Berning L, Bolscher JM, Demarta-Gatsi C, Henderson RWM, Huijs T, Koolen KMJ, Tumwebaze PK, Yeo T, Aguiar ACC, Angulo-Barturen I, Churchyard A, Baum J, Fernández BC, Fuchs A, Gamo FJ, Guido RVC, Jiménez-Diaz MB, Pereira DB, Rochford R, Roesch C, Sanz LM, Trevitt G, Witkowski B, Wittlin S, Cooper RA, Rosenthal PJ, Sauerwein RW, Schalkwijk J, Hermkens PHH, Bonnert RV, Campo B, Fidock DA, Llinás M, Niles JC, Kooij TWA, Dechering KJ. de Vries LE, et al. Among authors: wittlin s. Nat Commun. 2022 Apr 20;13(1):2158. doi: 10.1038/s41467-022-29688-5. Nat Commun. 2022. PMID: 35444200 Free PMC article.
Antimalarial Dibenzannulated Medium-Ring Keto Lactams.
Ren R, Wang X, Leas DA, Scheurer C, Hoevel S, Cal M, Chen G, Zhong L, Katneni K, Pham T, Patil R, Sil D, Walters MJ, Schulze TT, Neville AJ, Dong Y, Wittlin S, Kaiser M, Davis PH, Charman SA, Vennerstrom JL. Ren R, et al. Among authors: wittlin s. ACS Infect Dis. 2023 Oct 13;9(10):1964-1980. doi: 10.1021/acsinfecdis.3c00245. Epub 2023 Sep 11. ACS Infect Dis. 2023. PMID: 37695781
Our Exciting Journey to ACT-451840.
Boss C, Wittlin S. Boss C, et al. Among authors: wittlin s. Chimia (Aarau). 2021 Nov 24;75(11):916-922. doi: 10.2533/chimia.2021.916. Chimia (Aarau). 2021. PMID: 34798913 Free article.
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy.
Xie SC, Metcalfe RD, Dunn E, Morton CJ, Huang SC, Puhalovich T, Du Y, Wittlin S, Nie S, Luth MR, Ma L, Kim MS, Pasaje CFA, Kumpornsin K, Giannangelo C, Houghton FJ, Churchyard A, Famodimu MT, Barry DC, Gillett DL, Dey S, Kosasih CC, Newman W, Niles JC, Lee MCS, Baum J, Ottilie S, Winzeler EA, Creek DJ, Williamson N, Parker MW, Brand S, Langston SP, Dick LR, Griffin MDW, Gould AE, Tilley L. Xie SC, et al. Among authors: wittlin s. Science. 2022 Jun 3;376(6597):1074-1079. doi: 10.1126/science.abn0611. Epub 2022 Jun 2. Science. 2022. PMID: 35653481 Free PMC article.
The Plasmodium Lactate/H+ Transporter PfFNT Is Essential and Druggable In Vivo.
Davies H, Bergmann B, Walloch P, Nerlich C, Hansen C, Wittlin S, Spielmann T, Treeck M, Beitz E. Davies H, et al. Among authors: wittlin s. Antimicrob Agents Chemother. 2023 Aug 17;67(8):e0035623. doi: 10.1128/aac.00356-23. Epub 2023 Jul 10. Antimicrob Agents Chemother. 2023. PMID: 37428074 Free PMC article.
Diaryl Ureas as an Antiprotozoal Chemotype.
Leas DA, Sanford AG, Wu J, Cal M, Kaiser M, Wittlin S, Hemsley RM, Darner EB, Lui LM, Davis PH, Vennerstrom JL. Leas DA, et al. Among authors: wittlin s. ACS Infect Dis. 2021 Jun 11;7(6):1578-1583. doi: 10.1021/acsinfecdis.1c00135. Epub 2021 May 10. ACS Infect Dis. 2021. PMID: 33971090 Free PMC article.
Stochastic Protein Alkylation by Antimalarial Peroxides.
Jourdan J, Walz A, Matile H, Schmidt A, Wu J, Wang X, Dong Y, Vennerstrom JL, Schmidt RS, Wittlin S, Mäser P. Jourdan J, et al. Among authors: wittlin s. ACS Infect Dis. 2019 Dec 13;5(12):2067-2075. doi: 10.1021/acsinfecdis.9b00264. Epub 2019 Dec 2. ACS Infect Dis. 2019. PMID: 31626733
Arylmethylamino steroids as antiparasitic agents.
Krieg R, Jortzik E, Goetz AA, Blandin S, Wittlin S, Elhabiri M, Rahbari M, Nuryyeva S, Voigt K, Dahse HM, Brakhage A, Beckmann S, Quack T, Grevelding CG, Pinkerton AB, Schönecker B, Burrows J, Davioud-Charvet E, Rahlfs S, Becker K. Krieg R, et al. Among authors: wittlin s. Nat Commun. 2017 Feb 17;8:14478. doi: 10.1038/ncomms14478. Nat Commun. 2017. PMID: 28211535 Free PMC article.
Prodrugs of reverse fosmidomycin analogues.
Brücher K, Gräwert T, Konzuch S, Held J, Lienau C, Behrendt C, Illarionov B, Maes L, Bacher A, Wittlin S, Mordmüller B, Fischer M, Kurz T. Brücher K, et al. Among authors: wittlin s. J Med Chem. 2015 Feb 26;58(4):2025-35. doi: 10.1021/jm5019719. Epub 2015 Feb 12. J Med Chem. 2015. PMID: 25633870
168 results