Serene W. Chen - Search Results

Year	Number of Results
2015	1
2016	2
2017	3
2018	2
2019	3
2020	4
2021	4
2022	3
2023	2
2024	1

1

Current trends and challenges in the downstream purification of bispecific antibodies.

Chen SW, Zhang W. Chen SW, et al. Antib Ther. 2021 May 7;4(2):73-88. doi: 10.1093/abt/tbab007. eCollection 2021 Apr. Antib Ther. 2021. PMID: 34056544 Free PMC article. Review.

2

Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers.

Fusco G, Chen SW, Williamson PTF, Cascella R, Perni M, Jarvis JA, Cecchi C, Vendruscolo M, Chiti F, Cremades N, Ying L, Dobson CM, De Simone A. Fusco G, et al. Among authors: chen sw. Science. 2017 Dec 15;358(6369):1440-1443. doi: 10.1126/science.aan6160. Science. 2017. PMID: 29242346 Free article.

3

Manufacturability and functionality assessment of different formats of T-cell engaging bispecific antibodies.

Loh HP, Mahfut FB, Chen SW, Huang Y, Huo J, Zhang W, Lam KP, Xu S, Yang Y. Loh HP, et al. Among authors: chen sw. MAbs. 2023 Jan-Dec;15(1):2231129. doi: 10.1080/19420862.2023.2231129. MAbs. 2023. PMID: 37403264 Free PMC article.

4

Preparation of α-Synuclein Amyloid Assemblies for Toxicity Experiments.

Chen SW, Cremades N. Chen SW, et al. Methods Mol Biol. 2018;1779:45-60. doi: 10.1007/978-1-4939-7816-8_4. Methods Mol Biol. 2018. PMID: 29886526

5

Structure-Toxicity Relationship in Intermediate Fibrils from α-Synuclein Condensates.

Chen SW, Barritt JD, Cascella R, Bigi A, Cecchi C, Banchelli M, Gallo A, Jarvis JA, Chiti F, Dobson CM, Fusco G, De Simone A. Chen SW, et al. J Am Chem Soc. 2024 Apr 17;146(15):10537-10549. doi: 10.1021/jacs.3c14703. Epub 2024 Apr 3. J Am Chem Soc. 2024. PMID: 38567991 Free PMC article.

6

The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes and Cellular Toxicity.

Xu CK, Castellana-Cruz M, Chen SW, Du Z, Meisl G, Levin A, Mannini B, Itzhaki LS, Knowles TPJ, Dobson CM, Cremades N, Kumita JR. Xu CK, et al. Among authors: chen sw. Molecules. 2022 Feb 15;27(4):1293. doi: 10.3390/molecules27041293. Molecules. 2022. PMID: 35209093 Free PMC article.

7

Probing the Origin of the Toxicity of Oligomeric Aggregates of α-Synuclein with Antibodies.

Cascella R, Perni M, Chen SW, Fusco G, Cecchi C, Vendruscolo M, Chiti F, Dobson CM, De Simone A. Cascella R, et al. Among authors: chen sw. ACS Chem Biol. 2019 Jun 21;14(6):1352-1362. doi: 10.1021/acschembio.9b00312. Epub 2019 May 14. ACS Chem Biol. 2019. PMID: 31050886 Free PMC article.

8

The Toxicity of Misfolded Protein Oligomers Is Independent of Their Secondary Structure.

Vivoli Vega M, Cascella R, Chen SW, Fusco G, De Simone A, Dobson CM, Cecchi C, Chiti F. Vivoli Vega M, et al. Among authors: chen sw. ACS Chem Biol. 2019 Jul 19;14(7):1593-1600. doi: 10.1021/acschembio.9b00324. Epub 2019 Jul 5. ACS Chem Biol. 2019. PMID: 31074957

9

Defining α-synuclein species responsible for Parkinson's disease phenotypes in mice.

Froula JM, Castellana-Cruz M, Anabtawi NM, Camino JD, Chen SW, Thrasher DR, Freire J, Yazdi AA, Fleming S, Dobson CM, Kumita JR, Cremades N, Volpicelli-Daley LA. Froula JM, et al. Among authors: chen sw. J Biol Chem. 2019 Jul 5;294(27):10392-10406. doi: 10.1074/jbc.RA119.007743. Epub 2019 May 29. J Biol Chem. 2019. PMID: 31142553 Free PMC article.

10

The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells.

Cascella R, Chen SW, Bigi A, Camino JD, Xu CK, Dobson CM, Chiti F, Cremades N, Cecchi C. Cascella R, et al. Among authors: chen sw. Nat Commun. 2021 Mar 22;12(1):1814. doi: 10.1038/s41467-021-21937-3. Nat Commun. 2021. PMID: 33753734 Free PMC article.

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