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Ecdysone modulates both ultrastructural arrangement of hindgut and attachment of Trypanosoma cruzi DM 28c to the rectum cuticle of Rhodnius prolixus fifth-instar nymph.
Mendonça Lopes D D, Provençano AF AF, Mello CB CB, Feder D D, Albuquerque Cunha JMA JM, Sant'Anna NF NF, Curty Lechuga G GC, Cabral Bourguignon S SC, de Souza W W, de Souza Garcia E ES, Folly E EC, Azambuja P P, Gonzalez MS MS. Mendonça Lopes D D, et al. Among authors: cabral bourguignon s sc. Exp Parasitol. 2022 May-Jun;236-237:108247. doi: 10.1016/j.exppara.2022.108247. Epub 2022 Mar 17. Exp Parasitol. 2022. PMID: 35307367
Interactions between 4-aminoquinoline and heme: Promising mechanism against Trypanosoma cruzi.
Lechuga GC, Borges JC, Calvet CM, de Araújo HP, Zuma AA, do Nascimento SB, Motta MCM, Bernardino AMR, Pereira MCS, Bourguignon SC. Lechuga GC, et al. Among authors: bourguignon sc. Int J Parasitol Drugs Drug Resist. 2016 Dec;6(3):154-164. doi: 10.1016/j.ijpddr.2016.07.001. Epub 2016 Jul 14. Int J Parasitol Drugs Drug Resist. 2016. PMID: 27490082 Free PMC article.
Antileishmanial Activity of 2-Methoxy-4H-spiro-[naphthalene-1,2'-oxiran]-4-one (Epoxymethoxy-lawsone): A Promising New Drug Candidate for Leishmaniasis Treatment.
Oliveira LFG, Souza-Silva F, de Castro Côrtes LM, Cysne-Finkelstein L, de Souza Pereira MC, de Oliveira Junior FO, Pinho RT, Corte Real S, Bourguignon SC, Ferreira VF, Alves CR. Oliveira LFG, et al. Among authors: bourguignon sc. Molecules. 2018 Apr 10;23(4):864. doi: 10.3390/molecules23040864. Molecules. 2018. PMID: 29642584 Free PMC article.
The combination therapy of meglumine antimoniate and oxiranes (epoxy-α-lapachone and epoxymethyl-lawsone) enhance the leishmanicidal effect in mice infected by Leishmania (Leishmania) amazonensis.
Gonçalves-Oliveira LF, Souza-Silva F, de Castro Côrtes LM, Veloso LB, Santini Pereira BA, Cysne-Finkelstein L, Lechuga GC, Bourguignon SC, Almeida-Souza F, da Silva Calabrese K, Ferreira VF, Alves CR. Gonçalves-Oliveira LF, et al. Among authors: bourguignon sc. Int J Parasitol Drugs Drug Resist. 2019 Aug;10:101-108. doi: 10.1016/j.ijpddr.2019.08.002. Epub 2019 Aug 12. Int J Parasitol Drugs Drug Resist. 2019. PMID: 31430693 Free PMC article.
Epoxy-α-lapachone has in vitro and in vivo anti-leishmania (Leishmania) amazonensis effects and inhibits serine proteinase activity in this parasite.
Souza-Silva F, Bourguignon SC, Pereira BA, Côrtes LM, de Oliveira LF, Henriques-Pons A, Finkelstein LC, Ferreira VF, Carneiro PF, de Pinho RT, Caffarena ER, Alves CR. Souza-Silva F, et al. Among authors: bourguignon sc. Antimicrob Agents Chemother. 2015 Apr;59(4):1910-8. doi: 10.1128/AAC.04742-14. Epub 2015 Jan 12. Antimicrob Agents Chemother. 2015. PMID: 25583728 Free PMC article.