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Potential modulating effect of the Ascaris suum nicotinic acetylcholine receptor (nAChR) by compounds GSK575594A, diazepam and flumazenil discovered by structure-based virtual screening approach.
Stevanovic S, Marjanović DS, Trailović SM, Zdravković N, Perdih A, Nikolic K. Stevanovic S, et al. Among authors: trailovic sm. Mol Biochem Parasitol. 2021 Mar;242:111350. doi: 10.1016/j.molbiopara.2021.111350. Epub 2021 Jan 7. Mol Biochem Parasitol. 2021. PMID: 33422580
Carvacrol acts as a potent selective antagonist of different types of nicotinic acetylcholine receptors and enhances the effect of monepantel in the parasitic nematode Ascaris suum.
Marjanović DS, Zdravković N, Milovanović M, Trailović JN, Robertson AP, Todorović Z, Trailović SM. Marjanović DS, et al. Among authors: trailovic sm. Vet Parasitol. 2020 Feb;278:109031. doi: 10.1016/j.vetpar.2020.109031. Epub 2020 Jan 20. Vet Parasitol. 2020. PMID: 32032866
19 results