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Multiple endpoint in vitro toxicity assessment of a prototype heated tobacco product indicates substantially reduced effects compared to those of combustible cigarette.
Chapman F, Sticken ET, Wieczorek R, Pour SJ, Dethloff O, Budde J, Rudd K, Mason E, Czekala L, Yu F, Simms L, Nahde T, O'Connell G, Stevenson M. Chapman F, et al. Among authors: pour sj. Toxicol In Vitro. 2023 Feb;86:105510. doi: 10.1016/j.tiv.2022.105510. Epub 2022 Nov 11. Toxicol In Vitro. 2023. PMID: 36372310 Free article.
Twenty-eight day repeated exposure of human 3D bronchial epithelial model to heated tobacco aerosols indicates decreased toxicological responses compared to cigarette smoke.
Chapman F, Pour SJ, Wieczorek R, Trelles Sticken E, Budde J, Röwer K, Otte S, Mason E, Czekala L, Nahde T, O'Connell G, Simms L, Stevenson M. Chapman F, et al. Among authors: pour sj. Front Toxicol. 2023 Feb 16;5:1076752. doi: 10.3389/ftox.2023.1076752. eCollection 2023. Front Toxicol. 2023. PMID: 36875887 Free PMC article.