Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia

Emerg Infect Dis. 2021 May;27(5):1472-1476. doi: 10.3201/eid2705.204056.

Abstract

Understanding the immune response to Middle East respiratory syndrome coronavirus (MERS-CoV) is crucial for disease prevention and vaccine development. We studied the antibody responses in 48 human MERS-CoV infection survivors who had variable disease severity in Saudi Arabia. MERS-CoV-specific neutralizing antibodies were detected for 6 years postinfection.

Keywords: MERS; MERS-CoV; Middle East respiratory syndrome; Middle East respiratory syndrome coronavirus; Saudi Arabia; antibody responses; coronaviruses; disease severity; humans; longevity; patients; viruses; zoonoses.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibody Formation
  • Camelus
  • Coronavirus Infections* / epidemiology
  • Humans
  • Middle East Respiratory Syndrome Coronavirus*
  • Saudi Arabia / epidemiology