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Inhibition of extracellular HMGB1 attenuates hyperoxia-induced inflammatory acute lung injury.
Entezari M, Javdan M, Antoine DJ, Morrow DM, Sitapara RA, Patel V, Wang M, Sharma L, Gorasiya S, Zur M, Wu W, Li J, Yang H, Ashby CR, Thomas D, Wang H, Mantell LL. Entezari M, et al. Among authors: gorasiya s. Redox Biol. 2014 Jan 20;2:314-22. doi: 10.1016/j.redox.2014.01.013. eCollection 2014. Redox Biol. 2014. PMID: 24563849 Free PMC article.
The compromise of macrophage functions by hyperoxia is attenuated by ethacrynic acid via inhibition of NF-κB-mediated release of high-mobility group box-1.
Wang M, Gorasiya S, Antoine DJ, Sitapara RA, Wu W, Sharma L, Yang H, Ashby CR Jr, Vasudevan D, Zur M, Thomas DD, Mantell LL. Wang M, et al. Among authors: gorasiya s. Am J Respir Cell Mol Biol. 2015 Feb;52(2):171-82. doi: 10.1165/rcmb.2013-0544OC. Am J Respir Cell Mol Biol. 2015. PMID: 24992505 Free PMC article.