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Camptothecin structure simplification elaborated new imidazo[2,1-b]quinazoline derivative as a human topoisomerase I inhibitor with efficacy against bone cancer cells and colon adenocarcinoma.
Khodair AI, El-Hallouty SM, Cagle-White B, Abdel Aziz MH, Hanafy MK, Mowafy S, Hamdy NM, Kassab SE. Khodair AI, et al. Among authors: el hallouty sm. Eur J Med Chem. 2024 Feb 5;265:116049. doi: 10.1016/j.ejmech.2023.116049. Epub 2023 Dec 16. Eur J Med Chem. 2024. PMID: 38185054
Nonclassical antifolates, part 4. 5-(2-aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: synthesis, biological evaluation and molecular modeling study.
Hassan GS, El-Messery SM, Al-Omary FA, Al-Rashood ST, Shabayek MI, Abulfadl YS, Habib el-SE, El-Hallouty SM, Fayad W, Mohamed KM, El-Menshawi BS, El-Subbagh HI. Hassan GS, et al. Among authors: el hallouty sm. Eur J Med Chem. 2013 Aug;66:135-45. doi: 10.1016/j.ejmech.2013.05.039. Epub 2013 Jun 4. Eur J Med Chem. 2013. PMID: 23792351
11 results