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CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia.
Schmoellerl J, Barbosa IAM, Eder T, Brandstoetter T, Schmidt L, Maurer B, Troester S, Pham HTT, Sagarajit M, Ebner J, Manhart G, Aslan E, Terlecki-Zaniewicz S, Van der Veen C, Hoermann G, Duployez N, Petit A, Lapillonne H, Puissant A, Itzykson R, Moriggl R, Heuser M, Meisel R, Valent P, Sexl V, Zuber J, Grebien F. Schmoellerl J, et al. Among authors: sagarajit m. Blood. 2020 Jul 23;136(4):387-400. doi: 10.1182/blood.2019003267. Blood. 2020. PMID: 32344427 Free PMC article.
Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in Acute Myeloid Leukemia.
Mohanty S, Jyotsana N, Sharma A, Kloos A, Gabdoulline R, Othman B, Lai CK, Schottmann R, Mandhania M, Schmoellerl J, Grebien F, Ramsay E, Thomas A, Vornlocher HP, Ganser A, Thol F, Heuser M. Mohanty S, et al. Cancers (Basel). 2020 Sep 26;12(10):2766. doi: 10.3390/cancers12102766. Cancers (Basel). 2020. PMID: 32993115 Free PMC article.