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Page 1
Epigenetic dysregulation from chromosomal transit in micronuclei.
Agustinus AS, Al-Rawi D, Dameracharla B, Raviram R, Jones BSCL, Stransky S, Scipioni L, Luebeck J, Di Bona M, Norkunaite D, Myers RM, Duran M, Choi S, Weigelt B, Yomtoubian S, McPherson A, Toufektchan E, Keuper K, Mischel PS, Mittal V, Shah SP, Maciejowski J, Storchova Z, Gratton E, Ly P, Landau D, Bakhoum MF, Koche RP, Sidoli S, Bafna V, David Y, Bakhoum SF. Agustinus AS, et al. Nature. 2023 Jul;619(7968):176-183. doi: 10.1038/s41586-023-06084-7. Epub 2023 Jun 7. Nature. 2023. PMID: 37286593 Free PMC article.
Low Cell Number Proteomic Analysis Using In-Cell Protease Digests Reveals a Robust Signature for Cell Cycle State Classification.
Kelly V, Al-Rawi A, Lewis D, Kustatscher G, Ly T. Kelly V, et al. Mol Cell Proteomics. 2022 Jan;21(1):100169. doi: 10.1016/j.mcpro.2021.100169. Epub 2021 Nov 4. Mol Cell Proteomics. 2022. PMID: 34742921 Free PMC article.
Clustering of the pseudoperiodic proteins showed abundance patterns consistent with "waves" of protein degradation in late S, at the G2&M border, midmitosis, and at mitotic exit. These clusters were distinguished by significant differences in predicted nuclear l …
Clustering of the pseudoperiodic proteins showed abundance patterns consistent with "waves" of protein degradation in late S, at the …
Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents.
Yevglevskis M, Nathubhai A, Wadda K, Lee GL, Al-Rawi S, Jiao T, Mitchell PJ, James TD, Threadgill MD, Woodman TJ, Lloyd MD. Yevglevskis M, et al. Bioorg Chem. 2019 Nov;92:103263. doi: 10.1016/j.bioorg.2019.103263. Epub 2019 Sep 7. Bioorg Chem. 2019. PMID: 31536953
All tested precursor acids showed inhibitory activity against LnCaP, Du145 and PC3 cells at 500 M, but lacked activity at 100 M. This is the first extensive structure-activity relationship study on the influence of side-chain interactions on the potency of novel rat …
All tested precursor acids showed inhibitory activity against LnCaP, Du145 and PC3 cells at 500 M, but lacked activity at 100 M …
Spatial analysis of mandibular condyles in patients with temporomandibular disorders and normal controls using cone beam computed tomography.
Al-Rawi NH, Uthman AT, Sodeify SM. Al-Rawi NH, et al. Eur J Dent. 2017 Jan-Mar;11(1):99-105. doi: 10.4103/ejd.ejd_202_16. Eur J Dent. 2017. PMID: 28435374 Free PMC article.

RESULTS: Statistical significant differences were found between males and females of both groups regarding superior joint space (SJS), lateral joint space, A-P, and M-L condyle distance (P < 0.05). SJS, medial joint space (MJS), and eminence angle were greater (P < 0

…
RESULTS: Statistical significant differences were found between males and females of both groups regarding superior joint space (SJS), later …
High Sensitivity pH Sensor Based on Porous Silicon (PSi) Extended Gate Field-Effect Transistor.
Al-Hardan NH, Abdul Hamid MA, Ahmed NM, Jalar A, Shamsudin R, Othman NK, Kar Keng L, Chiu W, Al-Rawi HN. Al-Hardan NH, et al. Sensors (Basel). 2016 Jun 7;16(6):839. doi: 10.3390/s16060839. Sensors (Basel). 2016. PMID: 27338381 Free PMC article.
The prepared PSi has pore sizes in the range of 500 to 750 nm with a depth of approximately 42 m. The results of testing PSi for hydrogen ion sensing in different pH buffer solutions reveal that the PSi has a sensitivity value of 66 mV/pH that is considered a super Nernsti …
The prepared PSi has pore sizes in the range of 500 to 750 nm with a depth of approximately 42 m. The results of testing PSi for hydr …
Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis.
Giuliano M, Herrera S, Christiny P, Shaw C, Creighton CJ, Mitchell T, Bhat R, Zhang X, Mao S, Dobrolecki LE, Al-rawi A, Chen F, Veneziani BM, Zhang XH, Hilsenbeck SG, Contreras A, Gutierrez C, Jeselsohn RM, Rimawi MF, Osborne CK, Lewis MT, Schiff R, Trivedi MV. Giuliano M, et al. Breast Cancer Res. 2015 Jan 9;17(1):3. doi: 10.1186/s13058-014-0508-5. Breast Cancer Res. 2015. PMID: 25572662 Free PMC article.
Associations between the presence of CTCs, BM-DTCs, and LM were assessed by the Fisher's Exact and Cochran-Mantel-Haenszel tests. Two separate genetic signatures associated with the presence of CTC clusters and with lung metastatic potential were computed by using the expr …
Associations between the presence of CTCs, BM-DTCs, and LM were assessed by the Fisher's Exact and Cochran-Mantel-Haenszel tests. Two …