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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1970 2
1971 3
1972 3
1973 6
1974 12
1975 103
1976 139
1977 127
1978 130
1979 151
1980 201
1981 313
1982 310
1983 357
1984 388
1985 424
1986 422
1987 429
1988 475
1989 516
1990 503
1991 613
1992 571
1993 634
1994 655
1995 769
1996 779
1997 832
1998 831
1999 889
2000 846
2001 904
2002 887
2003 954
2004 972
2005 1043
2006 1010
2007 1046
2008 1155
2009 1175
2010 1212
2011 1326
2012 1337
2013 1359
2014 1473
2015 1388
2016 1097
2017 935
2018 1203
2019 1208
2020 1317
2021 1423
2022 1267
2023 1177
2024 384

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36,463 results

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Page 1
IgE and mast cells in allergic disease.
Galli SJ, Tsai M. Galli SJ, et al. Nat Med. 2012 May 4;18(5):693-704. doi: 10.1038/nm.2755. Nat Med. 2012. PMID: 22561833 Free PMC article. Review.
Immunoglobulin E (IgE) antibodies and mast cells have been so convincingly linked to the pathophysiology of anaphylaxis and other acute allergic reactions that it can be difficult to think of them in other contexts. ...Such potential roles include IgE-dependent regu …
Immunoglobulin E (IgE) antibodies and mast cells have been so convincingly linked to the pathophysiology of anaphylaxis and other acu …
Non-IgE-mediated anaphylaxis.
Cianferoni A. Cianferoni A. J Allergy Clin Immunol. 2021 Apr;147(4):1123-1131. doi: 10.1016/j.jaci.2021.02.012. J Allergy Clin Immunol. 2021. PMID: 33832694 Review.
Anaphylaxis is classically defined as an allergen-driven process that induces specific IgE and the activation of mast cells and basophils through the cross-linking of IgE receptors. However, it is clear that non-IgE-mediated pathways can induce symptoms indis …
Anaphylaxis is classically defined as an allergen-driven process that induces specific IgE and the activation of mast cells and basop …
IgE, IgE Receptors and Anti-IgE Biologics: Protein Structures and Mechanisms of Action.
McDonnell JM, Dhaliwal B, Sutton BJ, Gould HJ. McDonnell JM, et al. Annu Rev Immunol. 2023 Apr 26;41:255-275. doi: 10.1146/annurev-immunol-061020-053712. Epub 2023 Feb 3. Annu Rev Immunol. 2023. PMID: 36737596 Free article. Review.
Two well-known IgE receptors, the high-affinity FcepsilonRI and low-affinity CD23, mediate the activities of IgE. ...We describe recent research, highlighting structural studies of the IgE network of proteins to analyze the uniquely versatile activities of …
Two well-known IgE receptors, the high-affinity FcepsilonRI and low-affinity CD23, mediate the activities of IgE. ...We descri …
Anti-IgE therapy.
Brownell J, Casale TB. Brownell J, et al. Immunol Allergy Clin North Am. 2004 Nov;24(4):551-68, v. doi: 10.1016/j.iac.2004.06.002. Immunol Allergy Clin North Am. 2004. PMID: 15474858 Review.
IgE has a central role in the initiation of allergic hypersensitivity reactions. ...The primary mechanism of action of anti-IgE therapy is the reduction in serum levels of IgE and FcepsilonRI expression on mast cells and basophils....
IgE has a central role in the initiation of allergic hypersensitivity reactions. ...The primary mechanism of action of anti-IgE …
Abrogation and Homeostatic Restoration of IgE Responses by a Universal IgE Allergy CTL Vaccine-The Three Signal Self/Non-Self/Self (S/NS/S) Model.
Chen SS, Zhang H. Chen SS, et al. bioRxiv [Preprint]. 2023 Oct 17:2023.10.12.561777. doi: 10.1101/2023.10.12.561777. bioRxiv. 2023. PMID: 37904962 Free PMC article. Updated. Preprint.
The three signal model is proposed on the mechanisms underlying central tolerance, breaking tolerance and regaining peripheral tolerance via homeostasis concerning nECP as an efficacious and safe UAV to treat type I IgE-mediated hypersensitivity. ONE SENTENCE SUMMARY: Huma …
The three signal model is proposed on the mechanisms underlying central tolerance, breaking tolerance and regaining peripheral tolerance via …
IgE, Reed-Sternberg cells, and eosinophilia in Hodgkin's disease.
Samoszuk M, Ramzi E. Samoszuk M, et al. Leuk Lymphoma. 1993 Mar;9(4-5):315-9. doi: 10.3109/10428199309148528. Leuk Lymphoma. 1993. PMID: 8348067 Review.
Because eosinophils express a cell-surface receptor (CD23) for IgE and degranulate in the presence of IgE deposits, the extensive eosinophilia that is frequently present in Hodgkin's disease tumors is, at least in part, attributable to the IgE deposits …
Because eosinophils express a cell-surface receptor (CD23) for IgE and degranulate in the presence of IgE deposits, the extens …
IgE in the pathophysiology and therapy of food allergy.
Michelet M, Balbino B, Guilleminault L, Reber LL. Michelet M, et al. Eur J Immunol. 2021 Mar;51(3):531-543. doi: 10.1002/eji.202048833. Epub 2021 Feb 17. Eur J Immunol. 2021. PMID: 33527384 Free article. Review.
This review will discuss recent advances in the regulation of IgE production and IgE repertoires in food allergy. We will describe the current understanding of the role of IgE and its high-affinity receptor FcepsilonRI in food allergy and anaphylaxis, by revi …
This review will discuss recent advances in the regulation of IgE production and IgE repertoires in food allergy. We will desc …
IgE class-specific regulatory factor(s) and Fc epsilon receptors on lymphocytes.
Suemura M, Kishimoto T. Suemura M, et al. Int Rev Immunol. 1987 Jan;2(1):27-42. doi: 10.3109/08830188709044745. Int Rev Immunol. 1987. PMID: 2976798 Review.
The IgE isotype-specific regulatory factor(s) of rodents as well as humans was shown to have an affinity to IgE molecules, suggesting that the factor(s) are Fc epsilon receptors (Fc epsilon R) on lymphocytes or include a fragment of Fc epsilon R. ...Th …
The IgE isotype-specific regulatory factor(s) of rodents as well as humans was shown to have an affinity to IgE molecul …
Parasite allergens.
Caraballo L, Coronado S. Caraballo L, et al. Mol Immunol. 2018 Aug;100:113-119. doi: 10.1016/j.molimm.2018.03.014. Epub 2018 Mar 24. Mol Immunol. 2018. PMID: 29588070 Review.
Human IgE against helminths is a normal component of the whole protective response elicitesd during infection, when specific IgE to a great number of antigens is produced; however, few of those IgE binding components are actually allergens. ...Characterized A …
Human IgE against helminths is a normal component of the whole protective response elicitesd during infection, when specific IgE …
Accuracy of specific IgE antibody assays for diagnosis of cow's milk allergy.
Ahlstedt S, Holmquist I, Kober A, Perborn H. Ahlstedt S, et al. Ann Allergy Asthma Immunol. 2002 Dec;89(6 Suppl 1):21-5. doi: 10.1016/s1081-1206(10)62118-7. Ann Allergy Asthma Immunol. 2002. PMID: 12487200 Review.
Assays that detect all antibodies present in the serum sample and that demonstrate parallelism between dilutions of specific IgE antibodies and total IgE concentration also allow quantitative determinations of specific IgE antibodies. Such specific IgE …
Assays that detect all antibodies present in the serum sample and that demonstrate parallelism between dilutions of specific IgE anti …
36,463 results
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