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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1863 1
1884 2
1889 5
1893 2
1895 1
1896 2
1897 1
1898 1
1899 2
1900 1
1905 2
1908 1
1909 5
1910 4
1911 1
1912 1
1914 1
1915 12
1916 15
1917 8
1918 2
1919 6
1920 8
1921 4
1922 12
1923 8
1924 6
1925 13
1926 14
1927 6
1928 12
1929 9
1930 4
1931 5
1932 7
1933 8
1934 4
1935 5
1936 6
1937 9
1938 6
1939 4
1940 9
1941 6
1942 3
1944 4
1945 3
1946 4
1947 8
1948 6
1949 8
1950 2
1951 7
1952 10
1953 7
1954 4
1955 7
1956 10
1957 7
1958 5
1959 10
1960 14
1961 9
1962 2
1963 4
1964 10
1965 4
1966 8
1967 11
1968 11
1969 12
1970 6
1971 8
1972 7
1973 12
1974 20
1975 70
1976 54
1977 66
1978 81
1979 74
1980 83
1981 102
1982 115
1983 72
1984 101
1985 111
1986 95
1987 490
1988 1214
1989 1347
1990 1377
1991 1453
1992 1410
1993 1530
1994 1601
1995 1599
1996 1666
1997 1606
1998 1734
1999 1737
2000 2294
2001 1973
2002 2067
2003 2145
2004 2442
2005 2522
2006 2206
2007 2204
2008 2294
2009 2325
2010 2464
2011 2982
2012 3046
2013 3781
2014 5638
2015 7138
2016 6772
2017 6619
2018 8484
2019 8732
2020 9756
2021 10875
2022 10457
2023 9664
2024 2975

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127,200 results

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Page 1
PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson's disease.
Park H, Kam TI, Peng H, Chou SC, Mehrabani-Tabari AA, Song JJ, Yin X, Karuppagounder SS, Umanah GK, Rao AVS, Choi Y, Aggarwal A, Chang S, Kim H, Byun J, Liu JO, Dawson TM, Dawson VL. Park H, et al. Cell. 2022 May 26;185(11):1943-1959.e21. doi: 10.1016/j.cell.2022.04.020. Epub 2022 May 10. Cell. 2022. PMID: 35545089 Free PMC article.
Parthanatos-associated apoptosis-inducing factor (AIF) nuclease (PAAN), also known as macrophage migration inhibitor factor (MIF), is a member of the PD-D/E(X)K nucleases that acts as a final executioner in parthanatos. PAAN's role in Parkinson's disease (PD) and wh …
Parthanatos-associated apoptosis-inducing factor (AIF) nuclease (PAAN), also known as macrophage migration inhibitor factor (MIF), is a memb …
Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease.
Panicker N, Kam TI, Wang H, Neifert S, Chou SC, Kumar M, Brahmachari S, Jhaldiyal A, Hinkle JT, Akkentli F, Mao X, Xu E, Karuppagounder SS, Hsu ET, Kang SU, Pletnikova O, Troncoso J, Dawson VL, Dawson TM. Panicker N, et al. Neuron. 2022 Aug 3;110(15):2422-2437.e9. doi: 10.1016/j.neuron.2022.05.009. Epub 2022 Jun 1. Neuron. 2022. PMID: 35654037 Free PMC article.
Parkinson's disease (PD) is mediated, in part, by intraneuronal accumulation of alpha-synuclein aggregates andsubsequent death of dopamine (DA) neurons in the substantia nigra pars compacta (SNpc). ...
Parkinson's disease (PD) is mediated, in part, by intraneuronal accumulation of alpha-synuclein aggregates andsubsequent death of dop …
The Johns Hopkins Ciccarone Center's expanded 'ABC's approach to highlight 2020 updates in cardiovascular disease prevention.
Feldman DI, Wu KC, Hays AG, Marvel FA, Martin SS, Blumenthal RS, Sharma G. Feldman DI, et al. Am J Prev Cardiol. 2021 Apr 5;6:100181. doi: 10.1016/j.ajpc.2021.100181. eCollection 2021 Jun. Am J Prev Cardiol. 2021. PMID: 34327502 Free PMC article. Review.
In recent years, improvement in outcomes related to cardiovascular disease is in part due to the prioritization and progress of primary and secondary prevention efforts. The Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease expanded 'ABC's …
In recent years, improvement in outcomes related to cardiovascular disease is in part due to the prioritization and progress of primary and …
Transneuronal Propagation of Pathologic alpha-Synuclein from the Gut to the Brain Models Parkinson's Disease.
Kim S, Kwon SH, Kam TI, Panicker N, Karuppagounder SS, Lee S, Lee JH, Kim WR, Kook M, Foss CA, Shen C, Lee H, Kulkarni S, Pasricha PJ, Lee G, Pomper MG, Dawson VL, Dawson TM, Ko HS. Kim S, et al. Neuron. 2019 Aug 21;103(4):627-641.e7. doi: 10.1016/j.neuron.2019.05.035. Epub 2019 Jun 26. Neuron. 2019. PMID: 31255487 Free PMC article.
This study supports the Braak hypothesis in the etiology of idiopathic Parkinson's disease (PD)....
This study supports the Braak hypothesis in the etiology of idiopathic Parkinson's disease (PD)....
Neurodevelopmental Factors in Schizophrenia.
Jaaro-Peled H, Sawa A. Jaaro-Peled H, et al. Psychiatr Clin North Am. 2020 Jun;43(2):263-274. doi: 10.1016/j.psc.2020.02.010. Epub 2020 Apr 22. Psychiatr Clin North Am. 2020. PMID: 32439021 Review.
Targeting public neoantigens for cancer immunotherapy.
Pearlman AH, Hwang MS, Konig MF, Hsiue EH, Douglass J, DiNapoli SR, Mog BJ, Bettegowda C, Pardoll DM, Gabelli SB, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Pearlman AH, et al. Nat Cancer. 2021 May;2(5):487-497. doi: 10.1038/s43018-021-00210-y. Epub 2021 May 17. Nat Cancer. 2021. PMID: 34676374 Free PMC article. Review.
TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson's disease.
Seo BA, Kim D, Hwang H, Kim MS, Ma SX, Kwon SH, Kweon SH, Wang H, Yoo JM, Choi S, Kwon SH, Kang SU, Kam TI, Kim K, Karuppagounder SS, Kang BG, Lee S, Park H, Kim S, Yan W, Li YS, Kuo SH, Redding-Ochoa J, Pletnikova O, Troncoso JC, Lee G, Mao X, Dawson VL, Dawson TM, Ko HS. Seo BA, et al. Neuron. 2021 Dec 1;109(23):3758-3774.e11. doi: 10.1016/j.neuron.2021.09.031. Epub 2021 Oct 12. Neuron. 2021. PMID: 34644545 Free PMC article.
Impairment in glucocerebrosidase (GCase) is strongly associated with the development of Parkinson's disease (PD), yet the regulators responsible for its impairment remain elusive. ...
Impairment in glucocerebrosidase (GCase) is strongly associated with the development of Parkinson's disease (PD), yet the regulators …
Next generation strategies for preventing preterm birth.
Zierden HC, Shapiro RL, DeLong K, Carter DM, Ensign LM. Zierden HC, et al. Adv Drug Deliv Rev. 2021 Jul;174:190-209. doi: 10.1016/j.addr.2021.04.021. Epub 2021 Apr 23. Adv Drug Deliv Rev. 2021. PMID: 33895215 Free PMC article. Review.
Globally, 15 million infants are born prematurely, putting these children at an increased risk of mortality and lifelong health challenges. Currently in the U.S., there is only one FDA approved therapy for the prevention of preterm birth. ...Recently, however, Makena faile …
Globally, 15 million infants are born prematurely, putting these children at an increased risk of mortality and lifelong health challenges. …
Multi-omic analyses of changes in the tumor microenvironment of pancreatic adenocarcinoma following neoadjuvant treatment with anti-PD-1 therapy.
Li K, Tandurella JA, Gai J, Zhu Q, Lim SJ, Thomas DL 2nd, Xia T, Mo G, Mitchell JT, Montagne J, Lyman M, Danilova LV, Zimmerman JW, Kinny-Köster B, Zhang T, Chen L, Blair AB, Heumann T, Parkinson R, Durham JN, Narang AK, Anders RA, Wolfgang CL, Laheru DA, He J, Osipov A, Thompson ED, Wang H, Fertig EJ, Jaffee EM, Zheng L. Li K, et al. Cancer Cell. 2022 Nov 14;40(11):1374-1391.e7. doi: 10.1016/j.ccell.2022.10.001. Epub 2022 Oct 27. Cancer Cell. 2022. PMID: 36306792 Free PMC article.
Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3.
Mao X, Ou MT, Karuppagounder SS, Kam TI, Yin X, Xiong Y, Ge P, Umanah GE, Brahmachari S, Shin JH, Kang HC, Zhang J, Xu J, Chen R, Park H, Andrabi SA, Kang SU, Gonçalves RA, Liang Y, Zhang S, Qi C, Lam S, Keiler JA, Tyson J, Kim D, Panicker N, Yun SP, Workman CJ, Vignali DA, Dawson VL, Ko HS, Dawson TM. Mao X, et al. Science. 2016 Sep 30;353(6307):aah3374. doi: 10.1126/science.aah3374. Science. 2016. PMID: 27708076 Free PMC article.
Emerging evidence indicates that the pathogenesis of Parkinson's disease (PD) may be due to cell-to-cell transmission of misfolded preformed fibrils (PFF) of alpha-synuclein (alpha-syn). ...
Emerging evidence indicates that the pathogenesis of Parkinson's disease (PD) may be due to cell-to-cell transmission of misfolded pr …
127,200 results
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