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Page 1
Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders.
Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M. Johmura Y, et al. Among authors: mikawa r. Science. 2021 Jan 15;371(6526):265-270. doi: 10.1126/science.abb5916. Science. 2021. PMID: 33446552
Senolytic vaccination improves normal and pathological age-related phenotypes and increases lifespan in progeroid mice.
Suda M, Shimizu I, Katsuumi G, Yoshida Y, Hayashi Y, Ikegami R, Matsumoto N, Yoshida Y, Mikawa R, Katayama A, Wada J, Seki M, Suzuki Y, Iwama A, Nakagami H, Nagasawa A, Morishita R, Sugimoto M, Okuda S, Tsuchida M, Ozaki K, Nakanishi-Matsui M, Minamino T. Suda M, et al. Among authors: mikawa r. Nat Aging. 2021 Dec;1(12):1117-1126. doi: 10.1038/s43587-021-00151-2. Epub 2021 Dec 10. Nat Aging. 2021. PMID: 37117524
Cryptotanshinone is a candidate therapeutic agent for interstitial lung disease associated with a BRICHOS-domain mutation of SFTPC.
Hosokawa M, Mikawa R, Hagiwara A, Okuno Y, Awaya T, Yamamoto Y, Takahashi S, Yamaki H, Osawa M, Setoguchi Y, Saito MK, Abe S, Hirai T, Gotoh S, Hagiwara M. Hosokawa M, et al. Among authors: mikawa r. iScience. 2023 Aug 25;26(10):107731. doi: 10.1016/j.isci.2023.107731. eCollection 2023 Oct 20. iScience. 2023. PMID: 37701577 Free PMC article.
Protocol for assessing senescence-associated lung pathologies in mice.
Kawaguchi K, Hashimoto M, Mikawa R, Asai A, Sato T, Sugimoto M. Kawaguchi K, et al. Among authors: mikawa r. STAR Protoc. 2021 Dec 4;2(4):100993. doi: 10.1016/j.xpro.2021.100993. eCollection 2021 Dec 17. STAR Protoc. 2021. PMID: 34927099 Free PMC article.
15 results