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Page 1
Strategies for the development of conotoxins as new therapeutic leads.
Mar Drugs. 2013 Jun 28;11(7):2293-313. doi: 10.3390/md11072293.
Mar Drugs. 2013.
PMID: 23812174
Free PMC article.
Review.
Substituted Pyridazin-3(2 H)-ones as Highly Potent and Biased Formyl Peptide Receptor Agonists.
Deora GS, Qin CX, Vecchio EA, Debono AJ, Priebbenow DL, Brady RM, Beveridge J, Teguh SC, Deo M, May LT, Krippner G, Ritchie RH, Baell JB.
Deora GS, et al. Among authors: brady rm.
J Med Chem. 2019 May 23;62(10):5242-5248. doi: 10.1021/acs.jmedchem.8b01912. Epub 2019 May 13.
J Med Chem. 2019.
PMID: 31038950
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Synthesis of conformationally constrained benzoylureas as BH3-mimetics.
Brady RM, Hatzis E, Connor T, Street IP, Baell JB, Lessene G.
Brady RM, et al.
Org Biomol Chem. 2012 Jul 21;10(27):5230-7. doi: 10.1039/c2ob25618e. Epub 2012 May 30.
Org Biomol Chem. 2012.
PMID: 22648632
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Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 5 Based on Select Acetylenic Negative Allosteric Modulators.
Gregory KJ, Velagaleti R, Thal DM, Brady RM, Christopoulos A, Conn PJ, Lapinsky DJ.
Gregory KJ, et al. Among authors: brady rm.
ACS Chem Biol. 2016 Jul 15;11(7):1870-9. doi: 10.1021/acschembio.6b00026. Epub 2016 May 4.
ACS Chem Biol. 2016.
PMID: 27115427
Free PMC article.
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De novo design and synthesis of a μ-conotoxin KIIIA peptidomimetic.
Brady RM, Zhang M, Gable R, Norton RS, Baell JB.
Brady RM, et al.
Bioorg Med Chem Lett. 2013 Sep 1;23(17):4892-5. doi: 10.1016/j.bmcl.2013.06.086. Epub 2013 Jul 6.
Bioorg Med Chem Lett. 2013.
PMID: 23891024
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De-novo designed library of benzoylureas as inhibitors of BCL-XL: synthesis, structural and biochemical characterization.
Brady RM, Vom A, Roy MJ, Toovey N, Smith BJ, Moss RM, Hatzis E, Huang DC, Parisot JP, Yang H, Street IP, Colman PM, Czabotar PE, Baell JB, Lessene G.
Brady RM, et al.
J Med Chem. 2014 Feb 27;57(4):1323-43. doi: 10.1021/jm401948b. Epub 2014 Feb 5.
J Med Chem. 2014.
PMID: 24456288
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Benzoylureas as removable cis amide inducers: synthesis of cyclic amides via ring closing metathesis (RCM).
Brady RM, Khakham Y, Lessene G, Baell JB.
Brady RM, et al.
Org Biomol Chem. 2011 Feb 7;9(3):656-8. doi: 10.1039/c0ob00723d. Epub 2010 Nov 18.
Org Biomol Chem. 2011.
PMID: 21088766
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