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Page 1
Discovery, Function, and Therapeutic Targeting of Siglec-8.
Youngblood BA, Leung J, Falahati R, Williams J, Schanin J, Brock EC, Singh B, Chang AT, O'Sullivan JA, Schleimer RP, Tomasevic N, Bebbington CR, Bochner BS. Youngblood BA, et al. Among authors: falahati r. Cells. 2020 Dec 24;10(1):19. doi: 10.3390/cells10010019. Cells. 2020. PMID: 33374255 Free PMC article. Review.
A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation.
Schanin J, Gebremeskel S, Korver W, Falahati R, Butuci M, Haw TJ, Nair PM, Liu G, Hansbro NG, Hansbro PM, Evensen E, Brock EC, Xu A, Wong A, Leung J, Bebbington C, Tomasevic N, Youngblood BA. Schanin J, et al. Among authors: falahati r. Mucosal Immunol. 2021 Mar;14(2):366-376. doi: 10.1038/s41385-020-00336-9. Epub 2020 Aug 19. Mucosal Immunol. 2021. PMID: 32814824 Free PMC article.
AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice.
Youngblood BA, Brock EC, Leung J, Falahati R, Bryce PJ, Bright J, Williams J, Shultz LD, Greiner DL, Brehm MA, Bebbington C, Tomasevic N. Youngblood BA, et al. Among authors: falahati r. Int Arch Allergy Immunol. 2019;180(2):91-102. doi: 10.1159/000501637. Epub 2019 Aug 9. Int Arch Allergy Immunol. 2019. PMID: 31401630 Free PMC article.
14 results